Wang Fang, Li Jizhen, Yu Dexin, Wang Qing
Department of Radiology.
Department of Radiology, Shandong Mental Health Center, Jinan, China.
Medicine (Baltimore). 2018 Apr;97(17):e0336. doi: 10.1097/MD.0000000000010336.
Chondroblastoma is a rare benign tumor, consisting of tissue resembling foetal cartilage, and arising in the epiphyses, or apophyses of long tubular bone. However, chondroblastoma of the cortex of the long bone metaphysis is extremely rare.A 15-year-old girl presented a 10-month history of intermittent knee pain and without mobility limitation. X ray, computed tomography (CT), and magnetic resonance imaging (MRI) showed a slightly expansile lytic lesion involving the metaphyseal cortex of the left distal femur. During histological examination, typical features of chondroblastoma were observed. Chondroblastoma was definitely and histologically diagnosed. Surgical procedures included intralesional tumor curettage and allograft bone implantation. The patient was discharged without any complications 1 week after surgery and there was no recurrence during a 10-month follow-up.This report describes a case of chondroblastoma in the metaphyseal cortex of the distal femur and serves as a reminder of the atypical anatomic location of chondroblastoma. Patients in an appropriate age group with typical imaging features may be diagnosed with chondroblastoma despite its rare location.
软骨母细胞瘤是一种罕见的良性肿瘤,由类似于胎儿软骨的组织构成,发生于长管状骨的骨骺或骨突。然而,长骨干骺端皮质的软骨母细胞瘤极为罕见。一名15岁女孩有10个月间歇性膝关节疼痛病史,且无活动受限。X线、计算机断层扫描(CT)和磁共振成像(MRI)显示左股骨远端干骺端皮质有一轻度膨胀性溶骨性病变。组织学检查时观察到软骨母细胞瘤的典型特征。软骨母细胞瘤得到明确的组织学诊断。手术操作包括病灶内肿瘤刮除和同种异体骨植入。患者术后1周无任何并发症出院,随访10个月无复发。本报告描述了一例发生于股骨远端干骺端皮质的软骨母细胞瘤病例,并提醒注意软骨母细胞瘤不典型的解剖位置。尽管位置罕见,但处于适当年龄组且具有典型影像学特征的患者仍可能被诊断为软骨母细胞瘤。