[Effect of levamisole on the activity of the blood T-lymphocytes and of factors they produce in patients with laryngeal cancer].

The functional activity of T-lymphocytes was studied in 20 donors and in 59 patients with laryngeal tumours, stages II to IV. A considerable decrease in the activity of T-lymphocytes was observed in patients with laryngeal cancer, stages III and IV. Levamisole increased the functional activity of T-lymphocytes in vitro. It was found that spontaneous rosette-formation, PHA-induced lymphocyte proliferation and gamma-interferon production increased while the activity of suppressor T-lymphocytes induced by concanavalin A decreased.