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即时的渴望变化预测吸烟复发行为:一项实验室研究。

Momentary changes in craving predict smoking lapse behavior: a laboratory study.

机构信息

Department of Psychology, University at Buffalo, The State University of New York, 206B Park Hall, Buffalo, NY, 14260, USA.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

出版信息

Psychopharmacology (Berl). 2018 Jul;235(7):2001-2012. doi: 10.1007/s00213-018-4898-4. Epub 2018 Apr 27.

Abstract

RATIONALE

Current research on factors that predict smoking lapse behavior is limited in its ability to fully characterize the critical moments leading up to decisions to smoke.

OBJECTIVES

We used a validated and widely used experimental analogue for smoking lapse to assess how moment-to-moment dynamics of craving relate to decisions to smoke.

METHODS

Heavy smokers (N = 128, M age = 35.9) participated in a 50-min laboratory delay to smoking task on 2 consecutive days, earning money for each 5 min they remained abstinent or ending the task by choosing to smoke. Participants rated craving and negative affect levels immediately prior to each choice. Participants were randomized to smoking as usual (n = 50) or overnight abstinence (n = 50 successfully abstained, n = 22 failed abstaining) prior to session 2. Discrete-time hazard models were used to examine craving and negative affect as time-varying predictors of smoking.

RESULTS

Higher craving levels prior to smoking opportunities predicted increased risk of smoking. When controlling for craving levels, incremental increases in craving predicted increased smoking risk. Increases in negative affect incrementally predicted increased smoking risk at session 2 only. Smokers who failed to abstain were at a higher risk of smoking than those who successfully abstained, whereas abstinent and non-abstinent smokers did not differ in smoking risk.

CONCLUSIONS

Findings demonstrate an extension of the smoking lapse paradigm that can be utilized to capture momentary changes in craving that predict smoking behavior. Evaluations of nuanced craving experiences may inform clinical and pharmacological research on preventing smoking lapse and relapse.

摘要

背景

目前关于预测吸烟复发行为的因素的研究,其能力有限,无法充分描述导致吸烟决定的关键时刻。

目的

我们使用经过验证和广泛使用的吸烟复发实验模拟物来评估渴望的瞬间动态与吸烟决定之间的关系。

方法

重度吸烟者(N=128,M 年龄=35.9)连续两天在 50 分钟的实验室延迟吸烟任务中参与,每 5 分钟保持不吸烟就可以获得奖励,或者通过选择吸烟来结束任务。参与者在每次选择前立即评估渴望和负面情绪水平。参与者被随机分配到吸烟(n=50)或夜间禁欲(n=50 成功禁欲,n=22 禁欲失败),然后在第二天进行实验。离散时间风险模型用于检查渴望和负面情绪作为吸烟的时变预测因素。

结果

吸烟机会前较高的渴望水平预测了吸烟风险的增加。当控制渴望水平时,渴望的增量增加预测了吸烟风险的增加。仅在第 2 次会议时,负面情绪的增加才会递增预测吸烟风险。未能禁欲的吸烟者比成功禁欲的吸烟者吸烟风险更高,而禁欲和非禁欲的吸烟者在吸烟风险方面没有差异。

结论

研究结果扩展了吸烟复发的范式,可以用于捕捉预测吸烟行为的渴望的瞬间变化。对细微渴望体验的评估可能为预防吸烟复发和戒烟的临床和药理学研究提供信息。

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