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中老年自杀死亡者死后血中酒精含量:与自杀促成/危险因素、方式及其他药物毒理学的关联。

Postmortem blood alcohol content among late-middle aged and older suicide decedents: Associations with suicide precipitating/risk factors, means, and other drug toxicology.

机构信息

The University of Texas at Austin Steve Hicks School of Social Work, United States.

The University of Texas at Austin Steve Hicks School of Social Work, United States.

出版信息

Drug Alcohol Depend. 2018 Jun 1;187:311-318. doi: 10.1016/j.drugalcdep.2018.02.034. Epub 2018 Apr 10.

Abstract

BACKGROUND

This study examined blood alcohol content (BAC) among suicide decedents aged 50+ and its associations with suicide precipitating/risk factors, means, and other drug toxicology.

METHODS

The National Violent Death Reporting System, 2005-2015, provided data (N = 56,118 for all suicide decedents and N = 29,115 with alcohol test results). We used logistic regression models, with BAC > 0.0 (BAC positive) and BAC > = 0.08 (intoxication) as the dependent variables.

RESULTS

Almost a third of decedents who were tested for alcohol were BAC positive, and almost two-thirds of those who were positive had a BAC > = 0.08. Alcohol problems prior to suicide (AOR = 6.71, 95% CI = 6.24-7.21), relationship problems (AOR = 1.53, 95% CI = 1.44-1.63), and death/suicide of family/friends (AOR = 1.22, 95% CI = 1.11-1.35) were associated with greater odds of a positive BAC, but suicide means were not significantly associated with a positive BAC. Alcohol problems (AOR = 2.98, 95% CI = 2.68-3.31), relationship problems (AOR = 1.18, 95% CI = 1.06-1.30), firearm use (AOR = 1.85, 95% CI = 1.59-2.16), and hanging/suffocation (AOR = 1.38, 95% CI = 1.16-1.64) were associated with greater odds of a BAC > = 0.08. A toxicology positive for antidepressants, marijuana, cocaine, or amphetamines was associated with greater odds of a positive BAC; however, a toxicology positive for antidepressants, opiates, or amphetamines was associated with lower odds of a BAC > = 0.08. BAC > = 0.08 rates increased over the study period.

CONCLUSIONS

Alcohol intoxication may have contributed to using more violent suicide means. The significant association between relationship problems and intoxication before suicide calls for restricting access to alcohol and suicide means for individuals with these problems. Suicide prevention may require crisis counseling/support for acute life stressors and ongoing emotional support.

摘要

背景

本研究调查了 50 岁及以上自杀死亡者的血液酒精含量 (BAC) 及其与自杀诱发/风险因素、手段和其他药物毒理学的关系。

方法

国家暴力死亡报告系统,2005-2015 年,提供了数据(所有自杀死亡者为 N=56118,有酒精检测结果的为 N=29115)。我们使用逻辑回归模型,将 BAC>0.0(BAC 阳性)和 BAC≥0.08(中毒)作为因变量。

结果

近三分之一接受酒精检测的死亡者 BAC 阳性,近三分之二的阳性者 BAC≥0.08。自杀前的酒精问题(AOR=6.71,95%CI=6.24-7.21)、人际关系问题(AOR=1.53,95%CI=1.44-1.63)和家人/朋友的死亡/自杀(AOR=1.22,95%CI=1.11-1.35)与 BAC 阳性的可能性更大相关,但自杀手段与 BAC 阳性无显著相关性。酒精问题(AOR=2.98,95%CI=2.68-3.31)、人际关系问题(AOR=1.18,95%CI=1.06-1.30)、枪支使用(AOR=1.85,95%CI=1.59-2.16)和悬挂/窒息(AOR=1.38,95%CI=1.16-1.64)与 BAC≥0.08 的可能性更大相关。抗抑郁药、大麻、可卡因或安非他命的毒理学阳性与 BAC 阳性的可能性更大相关;然而,抗抑郁药、阿片类药物或安非他命的毒理学阳性与 BAC≥0.08 的可能性更小相关。BAC≥0.08 的比率在研究期间有所增加。

结论

酒精中毒可能导致更暴力的自杀手段。人际关系问题与自杀前中毒之间的显著关联,呼吁限制有这些问题的个体获得酒精和自杀手段。自杀预防可能需要为急性生活应激源和持续的情感支持提供危机咨询/支持。

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