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原发性全髋关节置换术治疗夏科氏关节炎相关并发症发生率高,但临床结果改善。

Primary Total Hip Arthroplasty for Charcot Arthropathy is Associated With High Complications but Improved Clinical Outcomes.

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

J Arthroplasty. 2018 Sep;33(9):2912-2918. doi: 10.1016/j.arth.2018.04.002. Epub 2018 Apr 10.

Abstract

BACKGROUND

Neuropathic (Charcot) arthropathy of the hip is rare but can lead to joint destruction, bone loss, and dysfunction. While total hip arthroplasty (THA) may be considered a treatment option, only very limited data in the form of case reports are available on the results of THA. The goal of this study was to analyze the outcomes of primary THA for Charcot arthropathy with emphasis on implant survivorship, complications, and clinical outcomes.

METHODS

Eleven patients undergoing 12 primary THAs for Charcot arthropathy from 2007 to 2014 were retrospectively reviewed. All patients had a severe underlying neuropathy and clear radiographic evidence of Charcot arthropathy. Mean age was 54 years with 4 patients being female. Mean follow-up was 5 years.

RESULTS

Survivorship free of any revision was 75% at both 2 and 5 years. Three THAs (3/12) were revised: 2 for recurrent instability and 1 for femoral component loosening. Survivorship free of any reoperation was 67% at both 2 and 5 years. One additional THA underwent open reduction and internal fixation of a Vancouver B periprosthetic fracture. The overall complication rate (including revisions and reoperations) was high at 58% with 3 recurrent dislocations, 2 periprosthetic fractures, 1 femoral component loosening, and 1 delayed wound healing. Harris Hip Scores improved from a mean of 43 preoperatively to 81 postoperatively (P < .001).

CONCLUSION

In this study, the largest to date, we found that patients undergoing primary THA for Charcot arthropathy have a significant improvement in clinical outcomes but that there was a high risk of early complications and revisions, mostly related to recurrent instability. Specific precautions to avoid early complications, namely utilization of components that provide robust fixation and strategies that provide enhanced hip stability, should be considered.

LEVEL OF EVIDENCE

Level IV.

摘要

背景

神经病变性(夏科)髋关节病比较罕见,但可导致关节破坏、骨丢失和功能障碍。全髋关节置换术(THA)可能是一种治疗选择,但仅有非常有限的病例报告形式的数据可用于评估 THA 的结果。本研究的目的是分析原发性夏科髋关节病的 THA 结果,重点关注假体的存活率、并发症和临床结果。

方法

回顾性分析了 2007 年至 2014 年间 11 例因夏科髋关节病行 12 例原发性 THA 的患者。所有患者均有严重的基础神经病变和明确的夏科髋关节病的放射影像学证据。平均年龄为 54 岁,其中 4 例为女性。平均随访时间为 5 年。

结果

2 年和 5 年时无任何翻修的生存率分别为 75%。3 例 THA(3/12)进行了翻修:2 例因再次不稳定,1 例因股骨组件松动。2 年和 5 年时无任何再手术的生存率分别为 67%。另外 1 例 THA 因温哥华 B 型假体周围骨折行切开复位内固定术。总体并发症发生率(包括翻修和再手术)较高,为 58%,包括 3 例复发性脱位、2 例假体周围骨折、1 例股骨组件松动和 1 例伤口愈合延迟。髋关节 Harris 评分从术前的平均 43 分提高到术后的 81 分(P<0.001)。

结论

在这项迄今为止最大的研究中,我们发现,接受原发性 THA 治疗的夏科髋关节病患者的临床结果有显著改善,但早期并发症和翻修的风险较高,主要与再次不稳定有关。应考虑采取特定的预防措施来避免早期并发症,即使用能提供牢固固定的假体和增强髋关节稳定性的策略。

证据水平

IV 级。

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