Department of Pediatric, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.
Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.
J Infect Public Health. 2019 Mar-Apr;12(2):282-284. doi: 10.1016/j.jiph.2018.04.001. Epub 2018 Apr 26.
Actinomycosis is a rare infection in patients younger than 10years of age. It mainly affects the cervicofacial region, but many other sites of infection have been recognized. About 70% of infections are due to either Actinomyces israelii or Actinomyces gerencseriae. Actinomyces neuii was first described in 1985 in two patients with post cataract endophthalmitis, A. neuii represents 17% of clinical Actinomyces isolates. Several reports indicated a well-known association between Actinomyces infections and Intrauterine devices (IUD). We are reporting a case of neonatal sepsis due to A. neuii as a first case reported from Saudi Arabia. It was thought to be the cause of the premature labor and neonatal sepsis. The prevalence of Actinomyces infection is likely underestimated and additional premature labors and abortions could have been caused by Actinomyces infections that were never detected. More studies are needed to confirm the association of maternal Actinomyces infections with preterm labor.
放线菌病在 10 岁以下的患者中较为罕见。它主要影响头颈部区域，但已认识到许多其他感染部位。约 70%的感染是由放线菌以色列亚种或放线菌龋齿亚种引起的。1985 年首次在两名患有白内障后眼内炎的患者中描述了放线菌纽伊氏菌，放线菌纽伊氏菌占临床放线菌分离株的 17%。有几份报告表明放线菌感染与宫内节育器（IUD）之间存在密切关联。我们报告了一例由放线菌纽伊氏菌引起的新生儿败血症，这是沙特阿拉伯首例报告的病例。据认为，它是早产和新生儿败血症的原因。放线菌感染的流行率可能被低估了，可能还有其他由从未检测到的放线菌感染引起的早产和流产。需要进一步研究以证实母体放线菌感染与早产之间的关联。
