Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA.
Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA.
Psychosomatics. 2018 Jul-Aug;59(4):341-348. doi: 10.1016/j.psym.2018.03.009. Epub 2018 Mar 21.
The prevalence of pregnancy-associated insomnia is high. Although insomnia may flow from normal physiologic features of pregnancy, it may also be an early warning sign of a relapse, or a trigger for a relapse, of a psychiatric illness. Those at risk for psychiatric illnesses may require medications as well as behavioral and psychotherapeutic interventions, to prevent relapse in the perinatal period. Unfortunately, few reviews of psychotropics used to treat pregnancy-related sleep disorders exist.
We discuss issues related to sleep and sleep disorders in pregnancy in the context of co-morbid psychiatric illness, and review the literature on the commonly-used medications (e.g., benzodiazepines, sedative-hypnotics, antihistamines, trazodone, and melatonin) for insomnia during pregnancy.
妊娠相关失眠的患病率较高。尽管失眠可能源于妊娠的正常生理特征，但它也可能是精神疾病复发的早期预警信号，或者是精神疾病复发的触发因素。那些有精神疾病风险的人可能需要药物治疗以及行为和心理治疗干预，以预防围产期复发。不幸的是，很少有关于用于治疗与妊娠相关睡眠障碍的精神药物的综述。
我们在合并精神疾病的情况下讨论与妊娠相关的睡眠和睡眠障碍相关问题，并回顾有关苯二氮䓬类药物、镇静催眠药、抗组胺药、曲唑酮和褪黑素等常用于妊娠失眠的药物的文献。
