Department of Pathology, School of Medicine, The Union of Chambers and Commodity Exchanges of Turkey, University of Economics and Technology (TOBB ETU), TOBB ETU, Tıp Fakultesi Hastanesi, Yaşam Caddesi No:5, PK 06510, Ankara, Turkey.
Private Goren Pathology Laboratory, Sakarya Caddesi, No:1/64, Kızılay, Ankara, Turkey.
J Craniomaxillofac Surg. 2018 Jun;46(6):942-946. doi: 10.1016/j.jcms.2018.04.007. Epub 2018 Apr 11.
Most of the odontogenic keratocysts show an indolent behaviour like non-neoplastic lesions. For this reason, the odontogenic keratocyst was reclassified within the odontogenic cysts category in the WHO 2017 classification. Some odontogenic keratocysts may contain satellite cysts or solid squamoid islands within their wall. Recently, a solid form of odontogenic keratocyst has also been described which is composed entirely of multiple epithelial islands and small cysts in a collagenous stroma. The true nature of this variant is unclear yet. In this article, we present a series of 204 odontogenic keratocyst cases. Clinical and histologic findings of the cases in this series were described. These were also categorised according to the presence of satellite lesions. Additionally, the features of two cases of the solid form of odontogenic keratocysts were compared with those of the previous reports and other histologically similar odontogenic lesions. Current evidence suggests that this variant may be neoplastic and it differs from other odontogenic keratocysts, at least histologically. We believe diagnosing a solid lesion as a cyst is counterintuitive and the term "keratocystic odontogenic tumour" better describes this particular variant.
大多数牙源性角化囊肿表现为类似于非肿瘤性病变的惰性行为。因此，在 2017 年世界卫生组织分类中，牙源性角化囊肿被重新归类为牙源性囊肿类别。一些牙源性角化囊肿的囊壁内可能含有卫星囊肿或实性鳞片状岛。最近，也描述了一种实性牙源性角化囊肿，其完全由多个上皮岛和小囊肿组成，位于胶原基质中。这种变体的真正性质尚不清楚。在本文中，我们介绍了一系列 204 例牙源性角化囊肿病例。描述了该系列病例的临床和组织学发现。根据卫星病变的存在对这些病例进行了分类。此外，还将两例实性牙源性角化囊肿的特征与之前的报告和其他组织学上相似的牙源性病变进行了比较。目前的证据表明，这种变体可能是肿瘤性的，至少在组织学上与其他牙源性角化囊肿不同。我们认为将实性病变诊断为囊肿是违反直觉的，“角化囊性牙源性肿瘤”这一术语更能描述这种特殊变体。
