Shafie Lili, Esmaili Sara, Parirokh Masoud, Pardakhti Abbas, Nakhaee Nouzar, Abbott Paul V, Barghi Hamide
Pedodontist, Fellowship in Sedation and Hospital Dentistry, Kerman, Iran.
Department of Pediatric Dentistry, Dental School, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Iran Endod J. 2018 Spring;13(2):216-220. doi: 10.22037/iej.v13i2.16624.
Pain management following dental procedures, particularly pulpotomies and extraction, is of great importance in pediatric dentistry. The aim of this study was to investigate the efficacy of pre-treatment with ibuprofen on post-operative pain following pulpotomy of primary molars.
In a split mouth double-blinded randomized clinical trial, 49 children aging between 6-10 years old were given either ibuprofen or a placebo 45 min prior to the treatment. After pulpotomy and placement of a stainless steel crown (SSC), the pain level was evaluated using the Wong-Baker face visual analogue scale for up to 7 days post-treatment. McNemar and Wilcoxon tests were used for data analysis.
Forty-five patients were eligible to participate in this study. Pre-medication with ibuprofen significantly reduced pain during the first 24 h post-treatment (=0.032). However, there was no significant difference in the pain levels between placebo and ibuprofen groups at 48 and 72 h post-treatment (=0.154 and =0.197, respectively). The number of times patients needed analgesics in ibuprofen group was significantly lower compared to that in the placebo group (=0.008).
Pre-medication with ibuprofen resulted in less pain following pulpotomy and SSC placement in primary teeth.
牙科手术后的疼痛管理，尤其是牙髓切断术和拔牙后的疼痛管理，在儿童牙科中非常重要。本研究的目的是调查布洛芬预处理对乳牙牙髓切断术后术后疼痛的疗效。
在一项双盲随机临床试验中，49名6至10岁的儿童在治疗前45分钟接受布洛芬或安慰剂治疗。在进行牙髓切断术并放置不锈钢冠（SSC）后，使用面部表情视觉模拟量表评估治疗后长达7天的疼痛程度。采用McNemar检验和Wilcoxon检验进行数据分析。
45名患者符合本研究的参与条件。布洛芬预处理显著减轻了治疗后前24小时的疼痛（P=0.032）。然而，治疗后48小时和72小时，安慰剂组和布洛芬组的疼痛程度没有显著差异（分别为P=0.154和P=0.197）。与安慰剂组相比，布洛芬组患者需要镇痛药的次数显著减少（P=0.008）。
布洛芬预处理可减轻乳牙牙髓切断术和放置SSC后的疼痛。
