Sharifi Roohollah, Godiny Mostafa, Mozaffari Hamid Reza, Safaei Mohsen, Hatam Reza, Veisi Mahta
Department of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Oral and Maxillofacial Medicine, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Iran Endod J. 2019 Spring;14(2):96-103. doi: 10.22037/iej.v14i2.22531.
The failure rate of inferior alveolar nerve (IAN) block is high for mandibular molars with irreversible pulpitis. This double-blind, randomized, clinical trial aimed to assess the effect of topical application of Dentol drop on the rate of successful anaesthesia of mandibular molars with irreversible pulpitis due to deep carious lesions.
Seventy-two patients with mandibular first and second molars with irreversible pulpitis and deep cavitated carious lesions participated in this study. The patients were randomly assigned to the test and control groups (=36). In the test group, a cotton pellet, dipped in Dentol drop, was placed in the cavity for 10 min. A placebo was used in the same manner in the control group. Level of pain was measured before the intervention, 15 min after anaesthesia (when patients reported numbness at the corner of the mouth), during access cavity preparation, upon pulp exposure and after introduction of the initial file into the root canal; using a Heft-Parker "Visual Analog Scale" (VAS). Data were analysed using ANCOVA.
Levels of pain were recorded during access cavity preparation (<0.001), pulp exposure (<0.001) and file introduction into the canal (=0.018). In the test (Dentol) group, the obtained levels of pain were significantly lower than those of the corresponding values in the control group.
Topical application of Dentol drop increased the success rate of IAN block for root canal treatment of mandibular molars with irreversible pulpitis.
对于患有不可逆性牙髓炎的下颌磨牙，下牙槽神经（IAN）阻滞的失败率很高。这项双盲、随机临床试验旨在评估局部应用登托滴剂对因深龋病变导致不可逆性牙髓炎的下颌磨牙麻醉成功率的影响。
72例患有下颌第一和第二磨牙不可逆性牙髓炎及深龋洞病变的患者参与了本研究。患者被随机分为试验组和对照组（每组 = 36例）。在试验组中，将浸有登托滴剂的棉球置于龋洞内10分钟。对照组以相同方式使用安慰剂。在干预前、麻醉后15分钟（当患者报告口角麻木时）、开髓准备期间、牙髓暴露时以及将初始锉插入根管后，使用赫夫特 - 帕克“视觉模拟量表”（VAS）测量疼痛程度。数据采用协方差分析进行分析。
在开髓准备期间（<0.001）、牙髓暴露时（<0.001）和锉插入根管时（=0.018）记录了疼痛程度。在试验组（登托组）中，获得的疼痛程度显著低于对照组的相应值。
局部应用登托滴剂提高了患有不可逆性牙髓炎的下颌磨牙根管治疗时IAN阻滞的成功率。
