What does the Acute Respiratory Distress Syndrome trial (ART) teach us?-it is time for precision medicine and precision trials in critical care!
作者信息
Fumagalli Jacopo, Berra Lorenzo
机构信息
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, USA.
出版信息
J Thorac Dis. 2018 Mar;10(3):1300-1303. doi: 10.21037/jtd.2018.03.31.
Abstract
摘要
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What does the Acute Respiratory Distress Syndrome trial (ART) teach us?-it is time for precision medicine and precision trials in critical care!急性呼吸窘迫综合征试验（ART）给了我们什么启示？是时候在重症监护中推行精准医学和精准试验了！
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Effects of regional perfusion block in healthy and injured lungs.区域灌注阻滞对健康肺和损伤肺的影响。
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Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.肺复张与滴定式呼气末正压通气（PEEP）对比低PEEP对急性呼吸窘迫综合征患者死亡率的影响：一项随机临床试验
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Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.全球 50 个国家重症监护病房急性呼吸窘迫综合征患者的流行病学、治疗模式和死亡率。
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Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial.急性呼吸窘迫综合征的开放肺通气方法：一项初步随机对照试验
Crit Care Med. 2016 Jan;44(1):32-42. doi: 10.1097/CCM.0000000000001383.
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Acute cor pulmonale during protective ventilation for acute respiratory distress syndrome: prevalence, predictors, and clinical impact.急性呼吸窘迫综合征保护性通气期间发生急性肺心病：患病率、预测因素和临床影响。
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Physiological Effects of the Open Lung Approach in Patients with Early, Mild, Diffuse Acute Respiratory Distress Syndrome: An Electrical Impedance Tomography Study.开放肺策略对早期、轻度、弥漫性急性呼吸窘迫综合征患者的生理影响：一项电阻抗断层扫描研究
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Driving pressure and survival in the acute respiratory distress syndrome.驱动压与急性呼吸窘迫综合征患者的生存。
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Ventilator-induced lung injury.呼吸机相关性肺损伤
N Engl J Med. 2013 Nov 28;369(22):2126-36. doi: 10.1056/NEJMra1208707.
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