Brown Tim
Plast Reconstr Surg Glob Open. 2018 Mar 19;6(3):e1700. doi: 10.1097/GOX.0000000000001700. eCollection 2018 Mar.
Increased surface area of mammary implants is suggested as a causative agent for the development of biofilms, which may lead to capsular contraction. The aim of this study was to quantify the surface areas of round implants of different textures and examine how these data can be interpreted with regard to clinical observation.
Surface areas of textured round breast implants were calculated from previously reported confocal scanning microscopic assessment, and dimensions sourced from 3 breast implant manufacturers (McGhan, Mentor, and Silimed). Statistical comparisons were made between manufacturers for different implant volumes, profiles, and texturing.
There was a difference in surface area between manufacturers for all implant profiles and between manufacturers for equivalent volume implants (F (3, 253) = 2,828.87; < 0.001). Silimed polyurethane implants (mean area = 6.12 × 10 mm) was the highest. Natrelle (mean area = 1.2 × 10 mm) was the next highest, followed by Siltex (mean area = 4.8 × 10 mm). Mentor smooth implants (mean area = 4 × 10 mm) had the lowest mean surface area. There were no differences in surface area between the different profiles for Siltex, Silimed polyurethane, and Mentor smooth implants of the same volume.
The increased surface area produced by texturing, although different between manufacturers, seems to provide protection against capsular contraction. Correlation with clinical data indicates that the surface area alone cannot account for these differences. Smooth implants, which have the smallest surface area have the highest incidence of capsular contraction. These data are at odds with the biofilm theory of capsular contraction.
乳房植入物表面积增加被认为是生物膜形成的致病因素，生物膜可能导致包膜挛缩。本研究的目的是量化不同纹理圆形植入物的表面积，并研究如何根据临床观察来解释这些数据。
根据先前报道的共聚焦扫描显微镜评估计算纹理圆形乳房植入物的表面积，并从3家乳房植入物制造商（麦加恩、曼托和西利美）获取尺寸数据。对不同植入物体积、外形和纹理的制造商之间进行了统计比较。
所有植入物外形的制造商之间以及等效体积植入物的制造商之间表面积存在差异（F(3, 253) = 2828.87；P < 0.001）。西利美聚氨酯植入物（平均面积 = 6.12×10平方毫米）最高。娜绮丽（平均面积 = 1.2×10平方毫米）次之，其次是丝泰克（平均面积 = 4.8×10平方毫米）。曼托光滑植入物（平均面积 = 4×10平方毫米）的平均表面积最低。相同体积的丝泰克、西利美聚氨酯和曼托光滑植入物的不同外形之间表面积没有差异。
纹理产生的表面积增加，尽管制造商之间存在差异，但似乎能提供针对包膜挛缩的保护。与临床数据的相关性表明，仅表面积不能解释这些差异。表面积最小的光滑植入物包膜挛缩发生率最高。这些数据与包膜挛缩的生物膜理论不一致。
