Hackett G, Campbell S
King's College Hospital, London, UK.
Fetal Ther. 1986;1(2-3):124-5. doi: 10.1159/000262255.
The significance of intrauterine growth retardation (IUGR) and the methods currently available for assessment of fetal growth are briefly reviewed. The use of Doppler ultrasound assessment of the flow velocity waveform (FVW) of the uteroplacental waveform at 16-18 weeks of gestation is outlined. A pilot study of 127 pregnancies suggested that the sensitivity of the test was 67% and the specificity 65%. The prediction value of a negative test was 92%. Six of the 14 cases of IUGR had a normal FVW, but 3 of these had asymmetrical morphology. Four of the 8 IUGR cases with an abnormal FVW required delivery by cesarean section. The FVW also appears to be a valuable predictor of pregnancy-induced hypertension and fetal asphyxia.
简要回顾了宫内生长受限（IUGR）的意义以及目前可用于评估胎儿生长的方法。概述了在妊娠16 - 18周时使用多普勒超声评估子宫胎盘血流速度波形（FVW）的情况。一项针对127例妊娠的初步研究表明，该检测的敏感性为67%，特异性为65%。阴性检测的预测值为92%。14例IUGR病例中有6例FVW正常，但其中3例形态不对称。FVW异常的8例IUGR病例中有4例需要剖宫产。FVW似乎也是妊娠高血压和胎儿窒息的重要预测指标。
