Department of Pediatrics Harbor-UCLA Medical Center, USA.
Paradise Valley, AZ, USA.
Prog Biophys Mol Biol. 2018 Dec;140:41-48. doi: 10.1016/j.pbiomolbio.2018.04.005. Epub 2018 Apr 13.
Reduction of developmental biology to self-referential cell-cell communication offers a portal for understanding fundamental mechanisms of physiology as derived from physics through quantum mechanics. It is argued that self-referential organization is implicit to the Big Bang and its further expression is a recoil reaction to that Singularity. When such a frame is considered, in combination with experimental evidence for the importance of epigenetic inheritance, the unicellular state can be reappraised as the primary object of selection. This framework provides a significant shift in understanding the relationship between physics and biology, providing novel insights to the nature and origin of consciousness.
将发育生物学简化为自指的细胞间通讯,为通过量子力学从物理学中推导出生理学的基本机制提供了一个途径。有人认为,自指组织是大爆炸的固有特征,而其进一步的表达则是对奇点的反冲反应。当考虑到这样一个框架时,结合关于表观遗传继承重要性的实验证据,单细胞状态可以被重新评估为选择的主要对象。这个框架提供了对物理学和生物学之间关系的理解的重大转变,为意识的本质和起源提供了新的见解。