• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

眶额神经元对不确定奖励的统计参数进行预测编码。

Predictive coding of the statistical parameters of uncertain rewards by orbitofrontal neurons.

作者信息

O'Neill Martin, Schultz Wolfram

机构信息

Department of Experimental Psychology, University of Oxford, Tinsley Building, Mansfield Road, Oxford, OX1 3TA, UK.

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK.

出版信息

Behav Brain Res. 2018 Dec 14;355:90-94. doi: 10.1016/j.bbr.2018.04.041. Epub 2018 Apr 27.

DOI:10.1016/j.bbr.2018.04.041
PMID:29709608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6152578/
Abstract

Uncertain reward outcomes are characterised by statistical parameters that capture the numerical values of the underlying probability distributions of reward values, including the expected value, risk (variance) and probability. Here we show coding of an integrated expected value signal by single orbitofrontal neurons in response to visual cues predicting uncertain rewards. Separate subpopulations of orbitofrontal neurons predominantly code the prediction of one statistical parameter with few neurons showing combined coding. These signals are likely combined with subjective value signals to inform learning and decision making under conditions of uncertainty.

摘要

不确定的奖励结果具有一些统计参数,这些参数反映了奖励值潜在概率分布的数值,包括期望值、风险(方差)和概率。在此,我们展示了单个眶额神经元对预测不确定奖励的视觉线索做出反应时,对综合期望值信号的编码。眶额神经元的不同亚群主要编码一个统计参数的预测,只有少数神经元表现出联合编码。这些信号可能与主观价值信号相结合,以在不确定条件下为学习和决策提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/a3b14abe0252/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/be4fa0f98b0c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/bb8db954cdee/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/a3b14abe0252/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/be4fa0f98b0c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/bb8db954cdee/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584e/6152578/a3b14abe0252/gr4.jpg

相似文献

1
Predictive coding of the statistical parameters of uncertain rewards by orbitofrontal neurons.眶额神经元对不确定奖励的统计参数进行预测编码。
Behav Brain Res. 2018 Dec 14;355:90-94. doi: 10.1016/j.bbr.2018.04.041. Epub 2018 Apr 27.
2
Coding of reward risk by orbitofrontal neurons is mostly distinct from coding of reward value.眶额皮质神经元对奖赏风险的编码与对奖赏价值的编码大多是不同的。
Neuron. 2010 Nov 18;68(4):789-800. doi: 10.1016/j.neuron.2010.09.031.
3
Adaptation of reward sensitivity in orbitofrontal neurons.眶额皮质神经元奖赏敏感性的适应性。
J Neurosci. 2010 Jan 13;30(2):534-44. doi: 10.1523/JNEUROSCI.4009-09.2010.
4
Absence of spatial tuning in the orbitofrontal cortex.眶额皮层不存在空间调谐。
PLoS One. 2014 Nov 11;9(11):e112750. doi: 10.1371/journal.pone.0112750. eCollection 2014.
5
Orbitofrontal neurons infer the value and identity of predicted outcomes.眶额神经元推断预测结果的价值和特征。
Nat Commun. 2014 Jun 4;5:3926. doi: 10.1038/ncomms4926.
6
Overt Attention toward Appetitive Cues Enhances Their Subjective Value, Independent of Orbitofrontal Cortex Activity.过度关注食欲线索会提高它们的主观价值,而与眶额皮层活动无关。
eNeuro. 2019 Nov 1;6(6). doi: 10.1523/ENEURO.0230-19.2019. Print 2019 Nov/Dec.
7
Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems.人类奖励系统中与风险态度相关的不确定性编码不同的奖励价值编码。
J Neurophysiol. 2007 Feb;97(2):1621-32. doi: 10.1152/jn.00745.2006. Epub 2006 Nov 22.
8
Neuronal activity in primate orbitofrontal cortex reflects the value of time.灵长类动物眶额皮质中的神经元活动反映了时间的价值。
J Neurophysiol. 2005 Oct;94(4):2457-71. doi: 10.1152/jn.00373.2005. Epub 2005 Jun 15.
9
Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area.腹侧被盖区神经元活动的前额叶调节
Cereb Cortex. 2016 Oct;26(10):4057-4068. doi: 10.1093/cercor/bhv215. Epub 2015 Sep 22.
10
Supplementary eye field encodes option and action value for saccades with variable reward.补充眼区对具有可变奖励的扫视进行选项和动作值编码。
J Neurophysiol. 2010 Nov;104(5):2634-53. doi: 10.1152/jn.00430.2010. Epub 2010 Aug 25.

引用本文的文献

1
Adaptive reward representations integrate expected uncertainty signals in orbitofrontal cortex.适应性奖励表征整合眶额皮质中的预期不确定性信号。
Sci Adv. 2025 Jul 18;11(29):eadv9590. doi: 10.1126/sciadv.adv9590. Epub 2025 Jul 16.
2
Brain-correlates of processing local dependencies within a statistical learning paradigm.在统计学习范式中处理局部依赖关系的大脑相关性。
Sci Rep. 2022 Sep 12;12(1):15296. doi: 10.1038/s41598-022-19203-7.
3
Strategic decision making and prediction differences in autism.自闭症中的战略决策制定和预测差异。

本文引用的文献

1
Dopamine neurons learn relative chosen value from probabilistic rewards.多巴胺神经元从概率性奖励中学习相对选择价值。
Elife. 2016 Oct 27;5:e18044. doi: 10.7554/eLife.18044.
2
Decoding subjective decisions from orbitofrontal cortex.从眶额皮质解读主观决策
Nat Neurosci. 2016 Jul;19(7):973-80. doi: 10.1038/nn.4320. Epub 2016 Jun 6.
3
Economic choices reveal probability distortion in macaque monkeys.经济选择揭示了猕猴的概率扭曲。
PeerJ. 2022 Apr 21;10:e13328. doi: 10.7717/peerj.13328. eCollection 2022.
4
Excitatory-inhibitory tone shapes decision strategies in a hierarchical neural network model of multi-attribute choice.兴奋-抑制平衡调节在多属性选择的分层神经网络模型中的决策策略。
PLoS Comput Biol. 2021 Mar 11;17(3):e1008791. doi: 10.1371/journal.pcbi.1008791. eCollection 2021 Mar.
5
Advances in understanding meso-cortico-limbic-striatal systems mediating risky reward seeking.理解中脑边缘纹状体系统介导风险奖励寻求的进展。
J Neurochem. 2021 Jun;157(5):1547-1571. doi: 10.1111/jnc.15342. Epub 2021 Apr 19.
6
Shared and unique neural circuitry underlying temporally unpredictable threat and reward processing.时间不可预测的威胁和奖励处理的共享和独特神经回路。
Soc Cogn Affect Neurosci. 2021 Mar 24;16(4):370-382. doi: 10.1093/scan/nsab006.
7
Partial integration of the components of value in anterior cingulate cortex.前扣带皮层中价值成分的部分整合。
Behav Neurosci. 2020 Aug;134(4):296-308. doi: 10.1037/bne0000382.
8
Neural Correlates of Strategy Switching in the Macaque Orbital Prefrontal Cortex.猕猴眶额皮质中策略转换的神经相关物。
J Neurosci. 2020 Apr 8;40(15):3025-3034. doi: 10.1523/JNEUROSCI.1969-19.2020. Epub 2020 Feb 25.
9
Neural Mechanisms of Reward Prediction Error in Autism Spectrum Disorder.自闭症谱系障碍中奖励预测误差的神经机制
Autism Res Treat. 2019 Jul 1;2019:5469191. doi: 10.1155/2019/5469191. eCollection 2019.
J Neurosci. 2015 Feb 18;35(7):3146-54. doi: 10.1523/JNEUROSCI.3653-14.2015.
4
Dopamine reward prediction error responses reflect marginal utility.多巴胺奖励预测误差反应反映了边际效用。
Curr Biol. 2014 Nov 3;24(21):2491-500. doi: 10.1016/j.cub.2014.08.064. Epub 2014 Oct 2.
5
Integration of multiple determinants in the neuronal computation of economic values.在神经元对经济价值的计算中整合多种决定因素。
J Neurosci. 2014 Aug 27;34(35):11583-603. doi: 10.1523/JNEUROSCI.1235-14.2014.
6
Economic risk coding by single neurons in the orbitofrontal cortex.眶额皮质中单个神经元的经济风险编码
J Physiol Paris. 2015 Feb-Jun;109(1-3):70-7. doi: 10.1016/j.jphysparis.2014.06.002. Epub 2014 Jun 19.
7
Representation of outcome risk and action in the anterior caudate nucleus.前尾状核中的结果风险和行动表示。
J Neurosci. 2014 Feb 26;34(9):3279-90. doi: 10.1523/JNEUROSCI.3818-13.2014.
8
Dopamine prediction error responses integrate subjective value from different reward dimensions.多巴胺预测误差反应整合了来自不同奖励维度的主观价值。
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2343-8. doi: 10.1073/pnas.1321596111. Epub 2014 Jan 22.
9
Risk prediction error coding in orbitofrontal neurons.眶额皮质神经元的风险预测误差编码。
J Neurosci. 2013 Oct 2;33(40):15810-4. doi: 10.1523/JNEUROSCI.4236-12.2013.
10
Selective and graded coding of reward uncertainty by neurons in the primate anterodorsal septal region.灵长类动物前背侧隔区神经元对奖赏不确定性的选择性和分级编码。
Nat Neurosci. 2013 Jun;16(6):756-62. doi: 10.1038/nn.3398. Epub 2013 May 12.