Boiteau Laurent, Boivin Jean, Liard Annie, Quiclet-Sire Béatrice, Zard Samir Z
Laboratoire de Synthèse Organique associé au CNRS, Ecole Polytechnique, 91128 Palaiseau Cedex (France), Fax: (+33) 1 69-33-30-10.
Institut de Chimie des Substances Naturelles, F-91198 Gif-Sur-Yvette (France), Fax: (+33) 1 69-07-72-47.
Angew Chem Int Ed Engl. 1998 May 4;37(8):1128-1131. doi: 10.1002/(SICI)1521-3773(19980504)37:8<1128::AID-ANIE1128>3.0.CO;2-P.
Three different radical reactions were used in a short total synthesis of (±)-matrine (1). Two of the four six-membered rings and four new bonds were created in one radical cascade involving intermolecular addition followed by two successive cyclizations and transfer of a xanthate group.
在（±）-苦参碱（1）的简短全合成中使用了三种不同的自由基反应。在一个涉及分子间加成、随后进行两次连续环化和黄原酸酯基团转移的自由基串联反应中构建了四个六元环中的两个以及四条新键。
