Thippaiah Srinagesh Mannekote, Nagaraja Soumya, Birur Badari, Pandurangi Ananda
Dr. Thippaiah, Assistant Professor in Psychiatry, Zucker Hillside Hospital, NY. Dr. Nagaraja, Brookdale University Hospital & Medical Center, Brooklyn, NY. Dr. Birur, Assistant Professor, Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham. Dr. Pandurangi, Professor and Vice Chair, Virginia Commonwealth University, Department of Psychiatry, Richmond, VA.
Psychopharmacol Bull. 2018 Feb 5;48(2):29-33.
Stuttering Priapism is a recurrent, persistent penile erection in the absence of sexual desire due to altered genital hemodynamics, affecting the arterial component (high flow, non-ischemic) or the veno-occlusive mechanism (low flow, ischemic). Both typical and atypical antipsychotics increase the risk for priapism with greater implications in typicals than atypicals. Prompt recognition and treatment are important as 40% to 50% of patients with stuttering priapism may develop an erectile dysfunction if left untreated. There are several case reports in the literature about the association between psychotropic agents and priapism. However, there are no reports of successfully treating stuttering priapism using pseudoephedrine (sudafed) in the adult population. Here we present successful management of psychotropics induced stuttering priapism with pseudoephedrine in a male patient with schizophrenia.
间歇性阴茎异常勃起是指在无性欲的情况下,由于生殖器官血流动力学改变而反复出现、持续存在的阴茎勃起,可影响动脉成分(高流量、非缺血性)或静脉闭塞机制(低流量、缺血性)。典型和非典型抗精神病药物均会增加阴茎异常勃起的风险,其中典型抗精神病药物的影响比非典型药物更大。及时识别和治疗很重要,因为如果不治疗,40%至50%的间歇性阴茎异常勃起患者可能会发展为勃起功能障碍。文献中有几例关于精神药物与阴茎异常勃起之间关联的病例报告。然而,在成年人群中,尚无使用伪麻黄碱(Sudafed)成功治疗间歇性阴茎异常勃起的报告。在此,我们报告了一名患有精神分裂症的男性患者,使用伪麻黄碱成功治疗了精神药物引起的间歇性阴茎异常勃起。