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氟化物基和脱敏牙膏对牙本质通透性的体外影响。

In vitro effects of fluoride-based and desensitizing toothpastes on dentine permeability.

机构信息

Department of Orthodontics, Vita-Salute San Raffaele University, Milan, Italy.

Unit of Dentistry, Division of Orthodontics, Research area in Dentofacial Orthopedics and Orthodontics, IRCCS San Raffaele Scientific Institute, Milan, Italy.

出版信息

J Biol Regul Homeost Agents. 2018 Mar-Apr;32(2 Suppl. 2):51-58.

Abstract

This study aims to evaluate the effectiveness in reducing dentine permeability of three different toothpastes comparing with a sodium fluoride one. Dentine permeability was measured by a fluid filtration system. Dentin discs were randomized in four experimental groups and treated with different commercial toothpastes, as it follows. Group A: Sensodyne® Rapid, with strontium acetate; group B: Elmex Sensitive ProfessionalTM, with arginine and 450 ppm monofluoro-phosphate; group C: Colgate Total Advanced®, with 1450 ppm NaF; group D: AZ Pro-Expert®, with 1100 ppm SnF2. After brushing specimens of each groups were assigned to two subgroups and: 1) stored in artificial saliva (2 h) and treated with 6% citric acid for 1 min; 2) stored in artificial saliva for 24 h. SEM analysis was performed to investigate dentinal tubules occlusion of acid treated and stored in artificial saliva samples. Dentin permeability proved affected by dentifrice treatments. The toothpastes specifically formulated for hypersensitivity showed significant effects concerning decrease of dentine permeability. SEM observations demonstrated the presence of dentifrice particles on dentin surface and inside dentin tubules. Stannous fluoride treated samples exhibited the greater tubules occlusion.

摘要

本研究旨在评估三种不同牙膏与含氟牙膏相比减少牙本质渗透性的效果。牙本质渗透性通过液体过滤系统进行测量。牙本质圆盘随机分为四个实验组,用不同的商业牙膏处理,具体如下。组 A:舒适达®速效,含锶醋酸盐;组 B:艾美适敏感专业牙膏 TM,含精氨酸和 450 ppm 单氟磷酸;组 C:高露洁全效 ®,含 1450 ppm NaF;组 D: AZ Pro-Expert ®,含 1100 ppm SnF2。刷牙后,将每组标本分为两组:1)储存在人工唾液中(2 小时)并用 6%柠檬酸处理 1 分钟;2)储存在人工唾液中 24 小时。用 SEM 分析研究经酸处理和储存在人工唾液中的样本的牙本质小管闭塞情况。牙本质渗透性受牙膏处理的影响。专门为过敏症研制的牙膏在降低牙本质渗透性方面有显著效果。SEM 观察显示牙本质表面和牙本质小管内存在牙膏颗粒。用氟化亚锡处理的样本显示出更大的小管闭塞。

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