Department of Biochemistry, College of Medicine, University of Vermont, Burlington, VT 05401, USA.
Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Biomolecules. 2018 May 1;8(2):22. doi: 10.3390/biom8020022.
The 11th IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases was held in Clearwater Beach, Florida from 29 October⁻2 November 2017, with the aim of presenting the latest research on these enzymes and promoting interchange among aminoacyl-tRNA synthetase (ARS) researchers. Topics covered in the meeting included many areas of investigation, including ARS evolution, mechanism, editing functions, biology in prokaryotic and eukaryotic cells and their organelles, their roles in human diseases, and their application to problems in emerging areas of synthetic biology. In this report, we provide a summary of the major themes of the meeting, citing contributions from the oral presentations in the meeting.
第 11 届国际生物化学与分子生物学联合会聚焦于氨酰-tRNA 合成酶的会议于 2017 年 10 月 29 日至 11 月 2 日在佛罗里达州清水海滩举行,旨在展示这些酶的最新研究成果,并促进氨酰-tRNA 合成酶(ARS)研究人员之间的交流。会议涵盖的主题包括许多研究领域,包括 ARS 的进化、机制、编辑功能、原核细胞和真核细胞及其细胞器中的生物学功能、它们在人类疾病中的作用,以及它们在新兴合成生物学领域的应用。在本报告中,我们提供了会议的主要主题摘要,引用了会议口头报告中的贡献。