Liu Zhong, Zhang Deng-Yong, Lu Zheng, Zhang Pei, Sun Wan-Liang, Ma Xiang, Wu Hua, Wu Bin-Quan, Zhou Shuo
Department of General Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, People's Republic of China.
Department of Pharmacy, Bengbu Medical College, Bengbu, People's Republic of China.
Onco Targets Ther. 2018 Apr 23;11:2295-2301. doi: 10.2147/OTT.S162934. eCollection 2018.
We report a rare case of neuroendocrine tumor (NET) in the common bile duct (CBD). The patient is a 56-year-old female who presented to our department with symptoms of fever but without jaundice. A preoperative examination showed a tumor in the CBD. The tumor volume was almost 5.5 × 4.5 × 4 cm, which is the biggest NET in the CBD reported on PubMed. The imaging results (computed tomography [CT] and magnetic resonance imaging [MRI]) were not consistent with CBD adenocarcinoma. The tumor appeared to oppress the growth of the CBD rather than originate in the bile duct wall; combined with the low blood bilirubin index and lack of jaundice symptoms, the preoperative diagnosis was not clear. We performed a radical resection of the cholangiocarcinoma. The patient recovered well before going home. The pathology was NET (Grade 2). The patient showed no recurrence to date, without intravenous chemotherapy (8 months).
我们报告了一例罕见的胆总管神经内分泌肿瘤（NET）。患者为一名56岁女性，因发热症状前来我院就诊，但无黄疸。术前检查显示胆总管有肿瘤。肿瘤体积约为5.5×4.5×4 cm，是PubMed报道的胆总管中最大的NET。影像学检查结果（计算机断层扫描[CT]和磁共振成像[MRI]）与胆总管腺癌不符。肿瘤似乎压迫胆总管生长而非起源于胆管壁；结合低血胆红素指数和无黄疸症状，术前诊断不明确。我们对胆管癌进行了根治性切除。患者在出院前恢复良好。病理结果为NET（2级）。截至目前，患者未出现复发，未接受静脉化疗（8个月）。
