Tajima Takayuki, Tajiri Takuma, Mukai Masaya, Sugiyama Tomoko, Hasegawa Sayuri, Yamamoto Souichirou, Sadahiro Sotaro, Shimada Hideo, Makuuchi Hiroyasu
Department of Surgery, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Department of Pathology, Tokai University Hachioji Hospital, Hachioji, Tokyo 192-0032, Japan.
Oncol Lett. 2018 May;15(5):6393-6399. doi: 10.3892/ol.2018.8134. Epub 2018 Feb 28.
The purpose of the present study was to evaluate the recent trend of diagnosing appendiceal diseases through the analysis of appendectomy materials, stressing the importance of their pathological examination. A clinicopathological assessment of patients undergoing an appendectomy was conducted, based on the pathological examination of resected appendiceal lesions. Using a pathological database of surgical specimens from patients who underwent an appendectomy between March 2002 and September 2014, a retrospective, single-center analysis was performed. Among the 803 patients identified, 752 with appendiceal disease were selected for clinicopathological analysis. The diagnosis was inflammation (i.e. appendicitis) in 97.7% (n=735) and appendiceal neoplasm in 2.3% (n=17) of the patients. The most frequent type of appendiceal neoplasm was an intramucosal neoplasm (23.5%, n=4). In conclusion, the incidence of appendiceal neoplasms has increased in recent years, potentially due to increased and earlier detection by newer imaging modalities.
本研究的目的是通过对阑尾切除标本的分析来评估阑尾疾病诊断的近期趋势，强调其病理检查的重要性。基于切除的阑尾病变的病理检查，对接受阑尾切除术的患者进行了临床病理评估。利用2002年3月至2014年9月期间接受阑尾切除术患者的手术标本病理数据库，进行了一项回顾性单中心分析。在确定的803例患者中，选择752例患有阑尾疾病的患者进行临床病理分析。患者诊断为炎症（即阑尾炎）的占97.7%（n = 735），阑尾肿瘤的占2.3%（n = 17）。阑尾肿瘤最常见的类型是黏膜内肿瘤（23.5%，n = 4）。总之，近年来阑尾肿瘤的发病率有所增加，这可能是由于更新的成像方式提高了检测率且能更早地发现病变。
