R Priyadharshini, Vishali V M Shobini, Sonti Sulochana
Department of Pathology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Oct 3;16(10):e70778. doi: 10.7759/cureus.70778. eCollection 2024 Oct.
Appendiceal neoplasms (ANs) are uncommon, representing less than 1% of all gastrointestinal tumors. They are most often discovered incidentally during appendectomies performed for suspected acute appendicitis. Recent studies have reported an increase in the incidence of AN. Our study aimed to analyze the spectrum of AN and determine the cases discovered incidentally.
This retrospective descriptive study was performed over 10 years, from March 2014 to March 2024, at Saveetha Medical College and Hospital in Chennai, India. Complete enumeration sampling was performed, and tumor registries were reviewed to identify all cases of AN received during the study period. The corresponding clinical and radiological data were obtained from the hospital database, whereas histopathology records were used to evaluate tumor characteristics. Descriptive statistical analysis was employed, and the spectrum of AN was analyzed.
During the study period, 12 cases of AN were identified. Eleven cases (91.7%) were diagnosed from appendicectomy specimens, while one was from a right hemicolectomy specimen. Of these 12, nine cases (75%) were incidental findings. In our study, we found that there was a higher number of female cases, with nine out of twelve cases (75%) being female. Most patients presented with abdominal pain, and acute appendicitis was the most frequent preoperative diagnosis. Low-grade appendiceal mucinous neoplasm was the most common type encountered followed by other appendiceal tumors.
The incidence of AN has increased in recent years, with most cases being found incidentally. Given the increasing rate of incidental AN, it is vital to maintain vigilance in specimen analysis including comprehensive examination and precise grossing to ensure malignancies are not overlooked.
阑尾肿瘤（ANs）并不常见，占所有胃肠道肿瘤的比例不到1%。它们最常于因疑似急性阑尾炎而进行的阑尾切除术中偶然发现。最近的研究报告称AN的发病率有所上升。我们的研究旨在分析AN的谱系，并确定偶然发现的病例。
这项回顾性描述性研究于2014年3月至2024年3月在印度钦奈的萨维塔医学院和医院进行，为期10年。采用完全枚举抽样法，并查阅肿瘤登记处，以确定研究期间收治的所有AN病例。相应的临床和放射学数据从医院数据库中获取，而组织病理学记录则用于评估肿瘤特征。采用描述性统计分析方法，对AN的谱系进行分析。
在研究期间，共确定了12例AN病例。11例（91.7%）通过阑尾切除标本诊断，1例通过右半结肠切除标本诊断。在这12例中，9例（75%）为偶然发现。在我们的研究中，我们发现女性病例较多，12例中有9例（75%）为女性。大多数患者表现为腹痛，术前最常见的诊断是急性阑尾炎。低级别阑尾黏液性肿瘤是最常见的类型，其次是其他阑尾肿瘤。
近年来AN的发病率有所上升，大多数病例为偶然发现。鉴于偶然发现的AN发病率不断上升，在标本分析中保持警惕至关重要，包括全面检查和精确大体解剖，以确保不遗漏恶性肿瘤。
