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[左旋咪唑在缓慢进展型青少年精神分裂症患者联合治疗中的应用]

[Use of levamisole in the combined therapy of patients with slowly progressing juvenile schizophrenia].

作者信息

Sekirina T P, Mikheeva T V, Koliaskina G I, Tsutsul'kovskaia M Ia, Orlova V A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(7):90-4.

PMID:2973198
Abstract

Immunomodulating drug Levamisole was studied as a component in the combined treatment of juvenile slow progredient schizophrenia. Apart from normalizing the immune parameters, the drug improved the patients' clinical conditions. Most prominent was its clinical effect in patients with immune system sensitive to the drug. The patient's condition ameliorated in relation with the features of his initial state. Treating the patients with depressive-asthenic states has yielded the best results. Weaker was the effect on patients with obsessive-phobic disorders. The least curable were senesto-hypochondriac and dysmorphophobic disorders with sensitive delusions of relation.

摘要

免疫调节药物左旋咪唑作为青少年缓慢进展型精神分裂症联合治疗的一个组成部分进行了研究。除了使免疫参数正常化外,该药物还改善了患者的临床状况。最显著的是其对药物敏感的免疫系统患者的临床效果。患者的病情根据其初始状态的特征得到改善。治疗抑郁-虚弱状态的患者取得了最佳效果。对强迫-恐惧障碍患者的效果较弱。最难治愈的是伴有敏感关系妄想的衰老-疑病障碍和畸形恐惧症障碍。

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