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小肠原发性恶性黑色素瘤:2例报告并文献复习

Primary malignant melanoma of the small intestine: a report of 2 cases and a review of the literature.

作者信息

Yang Kwan Mo, Kim Chan Wook, Kim So-Woon, Lee Jong Lyul, Yoon Yong Sik, Park In Ja, Lim Seok-Byung, Yu Chang Sik, Kim Jin Cheon

机构信息

Department of General Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.

Division of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Ann Surg Treat Res. 2018 May;94(5):274-278. doi: 10.4174/astr.2018.94.5.274. Epub 2018 Apr 30.

Abstract

The majority of malignant melanomas in the small intestine are metastases from primary cutaneous lesions, it can also develop as a primary mucosal tumor in the gastrointestinal tract. In this report, we present rare cases of primary small bowel melanoma and review the current literature. A 78-year-old male presented with abdominal pain and CT enterography identified a ileal mass. A 79-year-old female presented with signs and symptoms of partial small bowel obstruction. Abdominopelvic CT and small bowel series revealed a obstructing mass in the distal jejunum. The masses were confirmed on laparotomy and histologically diagnosed as melanoma. Extensive postoperative clinical examination revealed no cutaneous lesions. A primary small bowel melanoma is an extremely rare neoplasm. A definite diagnosis can only be made after a thorough investigation has been made to exclude the coexistence of a primary lesion. Curative resection of the tumor remains the treatment of choice.

摘要

小肠中的大多数恶性黑色素瘤是原发性皮肤病变的转移瘤,它也可作为胃肠道原发性黏膜肿瘤发生。在本报告中,我们展示了原发性小肠黑色素瘤的罕见病例并回顾了当前文献。一名78岁男性因腹痛就诊,CT小肠造影发现回肠肿物。一名79岁女性出现部分小肠梗阻的体征和症状。腹盆腔CT和小肠造影显示空肠远端有梗阻性肿物。剖腹手术证实了肿物,并经组织学诊断为黑色素瘤。广泛的术后临床检查未发现皮肤病变。原发性小肠黑色素瘤是一种极其罕见的肿瘤。只有在进行彻底检查以排除原发性病变并存后才能做出明确诊断。肿瘤的根治性切除仍然是首选治疗方法。

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