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小肠原发性恶性黑色素瘤:一例报告。

Primary malignant melanoma of the small bowel: A case report.

作者信息

Marak James R, Kumar Tushant, Dwivedi Shivam, Verma Shashwat

机构信息

Department of Radiodiagnosis, Dr RMLIMS, Lucknow, Uttar Pradesh, 226010, India.

Department of Nuclear Medicine, Dr RMLIMS, Lucknow, Uttar Pradesh, 226010, India.

出版信息

Radiol Case Rep. 2024 Jan 6;19(3):1215-1221. doi: 10.1016/j.radcr.2023.12.005. eCollection 2024 Mar.

DOI:10.1016/j.radcr.2023.12.005
PMID:38259709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10801144/
Abstract

Malignant melanoma comprises 1%-3% of all malignant tumors of the gastrointestinal tract. The small bowel melanoma is an extremely rare malignancy. Very few cases have been reported in the literature. The small intestine is mostly affected by the metastatic tumors of the primary lesions especially cutaneous. This malignancy is diagnosed at the late stages as the patient remains asymptomatic. In this report we present a case of malignant melanoma arising from the small bowel in a 58-year-old male. There was no primary lesion in the eye, skin, anus, rectum or elsewhere in the body. The patient was treated with surgery. Afterward the patient presented to the emergency room with respiratory distress for which he was on ventilator support, sadly the patient died after 10 days. Malignant melanoma is an aggressive tumor and does not respond well to chemotherapy or radiotherapy.

摘要

恶性黑色素瘤占胃肠道所有恶性肿瘤的1% - 3%。小肠黑色素瘤是一种极其罕见的恶性肿瘤。文献中报道的病例极少。小肠主要受原发性病变尤其是皮肤转移性肿瘤的影响。这种恶性肿瘤在晚期才被诊断出来,因为患者一直没有症状。在本报告中,我们呈现了一例58岁男性小肠恶性黑色素瘤病例。眼部、皮肤、肛门、直肠或身体其他部位均未发现原发性病变。该患者接受了手术治疗。之后,患者因呼吸窘迫被送往急诊室,接受了呼吸机支持治疗,遗憾的是,患者在10天后死亡。恶性黑色素瘤是一种侵袭性肿瘤,对化疗或放疗反应不佳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/43ba40a87b26/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/9637506e7e67/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/a943088cac10/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/8a9ab55ae8e1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/97e1856d543a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/3a3b11f81c68/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/43ba40a87b26/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/9637506e7e67/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/a943088cac10/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/8a9ab55ae8e1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/97e1856d543a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/3a3b11f81c68/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bd8/10801144/43ba40a87b26/gr6.jpg

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Curr Radiopharm. 2020;13(1):56-62. doi: 10.2174/1874471012666191015101410.
2
Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception-A case report.转移性黑色素瘤:胃肠道出血和肠套叠的罕见病因——病例报告
Int J Surg Case Rep. 2018;53:144-146. doi: 10.1016/j.ijscr.2018.10.057. Epub 2018 Oct 29.
3
Primary malignant melanoma of the small intestine: a report of 2 cases and a review of the literature.
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Ann Surg Treat Res. 2018 May;94(5):274-278. doi: 10.4174/astr.2018.94.5.274. Epub 2018 Apr 30.
4
A Case of Primary Small Bowel Melanoma Diagnosed by Single-Balloon Enteroscopy.一例经单气囊小肠镜诊断的原发性小肠黑色素瘤
Clin Endosc. 2017 Jul;50(4):395-399. doi: 10.5946/ce.2016.153. Epub 2017 Jun 2.
5
Primary small bowel melanomas: fact or myth?原发性小肠黑色素瘤:事实还是虚构?
Ann Transl Med. 2016 Mar;4(6):113. doi: 10.21037/atm.2016.03.29.
6
Primary small bowel melanoma. A case report and a review of the literature.原发性小肠黑色素瘤。一例病例报告及文献综述。
G Chir. 2015 May-Jun;36(3):128-32.
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Gastrointestinal bleeding as presentation of small bowel metastases of malignant melanoma: Is surgery a good choice?以胃肠道出血为表现的恶性黑色素瘤小肠转移:手术是一个好的选择吗?
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