Timmers T K, Schadd E M, Monkelbaan J F, Meij V
Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Case Rep Gastroenterol. 2013 May 30;7(2):251-60. doi: 10.1159/000352017. Print 2013 May.
The occurrence of primary melanoma of the small intestine is rare. We describe the case of a 25-year-old man found to have a primary melanoma of the ileum. The patient presented with gradual onset of abdominal pain, fever, diarrhea, weight loss and fatigue. A preoperative diagnosis of a small intestinal tumor was based on the findings of computed tomography scanning. This diagnosis was confirmed at laparoto-my and a partial small bowel resection was performed. Histopathological examination of the resected specimen clarified the exact nature of the lesion, confirming the diagnosis of melanoma. Thorough postoperative investigation did not reveal a primary lesion in the skin, gastrointestinal tract, oculus or brain. Thus, we diagnosed this tumor as a primary lesion. One year after his operation, the patient remains well without any evidence of recurrence. Thus, we diagnosed this small bowel tumor as a primary melanoma of the small intestine.
小肠原发性黑色素瘤的发生较为罕见。我们描述了一名25岁男性被发现患有回肠原发性黑色素瘤的病例。该患者表现为腹痛、发热、腹泻、体重减轻和疲劳逐渐出现。术前基于计算机断层扫描的结果诊断为小肠肿瘤。该诊断在剖腹手术时得到证实，并进行了部分小肠切除术。对切除标本的组织病理学检查明确了病变的确切性质，确诊为黑色素瘤。术后全面检查未发现皮肤、胃肠道、眼部或脑部有原发性病变。因此，我们将此肿瘤诊断为原发性病变。患者术后一年情况良好，无任何复发迹象。因此，我们将此小肠肿瘤诊断为小肠原发性黑色素瘤。
