Pollo C F, Miot L D B, Meneguin S, Miot H A
Departamento de Dermatologia, SN. 2nd floor. Universidade Estadual Paulista (Unesp), 18618-000, Botucatu, SP, Brazil.
Departamento de enfermagem, SN. 1st floor Universidade Estadual Paulista (Unesp), 18618-000, Botucatu, SP, Brazil.
Int J Cosmet Sci. 2018 May 7. doi: 10.1111/ics.12464.
Melasma is a common chronic focal hypermelanosis that affects photexposed areas as face, mainly in women at fertile age. It inflicts a significant impact in quality of life; nevertheless, quality of life scores (e.g. MELASQoL) are not strongly correlated with clinical severity (e.g. MASI) in facial melasma, suggesting that different factors can influence the perception of disease beyond the clinical extension or the intensity of pigmentation.
To explore clinical and socio-demographic aspects that influences MELASQoL scores.
Cross-sectional study enrolling 155 adults (>18 y.o.) with facial melasma. MELASQoL, MASI, clinical and demographic information were assessed. The associations among factors were explored by multivariable methods.
The mean (SD) age of the participants was 39 (8) years, and 134 (86%) were females. The correlation (Spearman's rho) between MELASQoL and MASI was 0.35 (P < 0.05). In a multivariate regression, MELASQoL score was associated (P ≤ 0.05) to MASI score (β = 0.6), lower income (β = 6.8), be single (β = 4.2) and low education level (β = 5.0). At multiple correspondence analysis, MASI, sex, marriage, education and income were associated with MELASQoL, as well as MASI was associated to skin phototypes, income and education level.
The perception of life quality impairment in melasma is influenced by low scholarly, low family income, single marital status and greater clinical severity.
黄褐斑是一种常见的慢性局限性色素沉着过度疾病，累及面部等暴露于光照的部位，主要发生于育龄期女性。它对生活质量有重大影响；然而，面部黄褐斑的生活质量评分（如MELASQoL）与临床严重程度（如MASI）的相关性并不强，这表明除了临床范围或色素沉着强度外，不同因素可能会影响对疾病的认知。
探讨影响MELASQoL评分的临床和社会人口学因素。
对155名面部有黄褐斑的成年人（>18岁）进行横断面研究。评估MELASQoL、MASI、临床和人口学信息。通过多变量方法探讨各因素之间的关联。
参与者的平均（标准差）年龄为39（8）岁，其中134名（86%）为女性。MELASQoL与MASI之间的相关性（Spearman秩相关系数）为0.35（P<0.05）。在多变量回归分析中，MELASQoL评分与MASI评分（β=0.6）、低收入（β=6.8）、单身（β=4.2）和低教育水平（β=5.0）相关（P≤0.05）。在多重对应分析中，MASI、性别、婚姻状况、教育程度和收入与MELASQoL相关，同时MASI与皮肤光类型、收入和教育水平相关。
黄褐斑患者生活质量受损的认知受低学历、低家庭收入、单身婚姻状况和更高的临床严重程度影响。
