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牙本质过敏的诊室治疗:一项随机半口临床试验

In-office Treatments for Dentin Hypersensitivity: A Randomized Split-mouth Clinical Trial.

作者信息

Osmari Deise, Fraga Sara, Ferreira Ana Carolina de Oliveira, Eduardo Carlos de Paula, Marquezan Marcela, Silveira Bruno Lopes da

出版信息

Oral Health Prev Dent. 2018;16(2):125-130. doi: 10.3290/j.ohpd.a40299.

Abstract

PURPOSE

To assess the effectiveness of four in-office therapies used for the treatment of dentin hypersensitiviy (DH) after one single application.

MATERIALS AND METHODS

A randomised, controlled, split-mouth clinical trial was designed to evaluate the following treatments: 5% sodium fluoride varnish (positive control); 3% potassium oxalate; two-step self-etching adhesive; high power diode laser. Nineteen patients were selected and one tooth per quadrant was included in the study. After evaporative stimulation, pain was quantified by the Visual Analog Scale (VAS) at baseline, immediately after treatment, and after 15, 30 and 60 days.

RESULTS

Compared to the baseline values, fluoride varnish (p = 0.00) and potassium oxalate (p = 0.00) presented an immediate desensitising effect that remained constant at 15, 30 and 60 days. The high-power diode laser presented significant reduction in VAS scores after 15 days (p = 0.00), while in the self-etching adhesive group, a significant reduction in VAS scores was observed only after 60 days (p = 0.03). The change in VAS ([VAS x days] - VAS baseline) differed among the groups immediately after treatment, being higher in the fluoride varnish and lower in the adhesive groups, but no statistically significant difference was found at time intervals of 15, 30 and 60 days.

CONCLUSION

When an immediate desensitising effect is desired after one single application, fluoride varnish and potassium oxalate should be used. High-power diode laser and self-etching adhesive may not be clinically considered an appropriate desensitising therapy after one single application.

摘要

目的

评估单次应用四种诊室治疗方法治疗牙本质过敏症(DH)的效果。

材料与方法

设计一项随机、对照、双侧对照临床试验,以评估以下治疗方法:5%氟化钠 varnish(阳性对照);3%草酸钾;两步自酸蚀粘结剂;高功率二极管激光。选取19名患者,每个象限纳入一颗牙齿进行研究。在进行蒸发刺激后,通过视觉模拟评分法(VAS)在基线、治疗后即刻、15天、30天和60天后对疼痛进行量化。

结果

与基线值相比,氟化钠 varnish(p = 0.00)和草酸钾(p = 0.00)呈现即刻脱敏效果,在15天、30天和60天时保持不变。高功率二极管激光在15天后VAS评分显著降低(p = 0.00),而在自酸蚀粘结剂组中,仅在60天后观察到VAS评分显著降低(p = 0.03)。治疗后即刻,各治疗组间VAS的变化([VAS×天数] - VAS基线)有所不同,氟化钠 varnish组变化较高,粘结剂组变化较低,但在15天、30天和60天时间点未发现统计学显著差异。

结论

若单次应用后需要即刻脱敏效果,应使用氟化钠 varnish和草酸钾。高功率二极管激光和自酸蚀粘结剂单次应用后在临床上可能不被视为合适的脱敏治疗方法。

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