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铜(I)催化的三组分点击/过硫化物级联反应:三唑二硫醚的区域选择性合成。

Copper(I)-Catalyzed Three-Component Click/Persulfuration Cascade: Regioselective Synthesis of Triazole Disulfides.

机构信息

Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering , Shandong University , Jinan 250100 , People's Republic of China.

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry , Chinese Academy of Sciences , Shanghai 200032 , China.

出版信息

Org Lett. 2018 May 18;20(10):2956-2959. doi: 10.1021/acs.orglett.8b01002. Epub 2018 May 8.

Abstract

A copper(I)-catalyzed three-component CuAAC/persulfuration reaction providing rapid access to asymmetric triazole disulfides has been developed. The interrupted click reaction shows broad substrate scope, complete regioselectivity, and excellent functional group tolerability.

摘要

发展了一种铜(I)催化的三组分 CuAAC/过硫化反应,为不对称三唑二硫化物提供了快速的合成途径。该中断点击反应具有广泛的底物范围、完全的区域选择性和优异的官能团耐受性。

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