Department of Radiation Oncology, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, 213003, People's Republic of China.
Sci Rep. 2018 May 8;8(1):7270. doi: 10.1038/s41598-018-25644-w.
Breast-conserving surgery (BCS) plus postoperative radiotherapy has become the standard treatment for early-stage breast cancer. The aim of this study was to compare the setup accuracy of optical surface imaging by the Sentinel system with cone-beam computerized tomography (CBCT) imaging currently used in our clinic for patients received BCS. Two optical surface scans were acquired before and immediately after couch movement correction. The correlation between the setup errors as determined by the initial optical surface scan and CBCT was analyzed. The deviation of the second optical surface scan from the reference planning CT was considered an estimate for the residual errors for the new method for patient setup correction. The consequences in terms for necessary planning target volume (PTV) margins for treatment sessions without setup correction applied. We analyzed 145 scans in 27 patients treated for early stage breast cancer. The setup errors of skin marker based patient alignment by optical surface scan and CBCT were correlated, and the residual setup errors as determined by the optical surface scan after couch movement correction were reduced. Optical surface imaging provides a convenient method for improving the setup accuracy for breast cancer patient without unnecessary imaging dose.
保乳手术（BCS）加术后放疗已成为早期乳腺癌的标准治疗方法。本研究旨在比较 Sentinel 系统光学表面成像与我们临床目前使用的锥形束计算机断层扫描（CBCT）成像在接受 BCS 的患者中的摆位准确性。在进行治疗床运动校正之前和之后立即采集两次光学表面扫描。分析由初始光学表面扫描确定的与 CBCT 之间的设置误差的相关性。第二次光学表面扫描与参考计划 CT 的偏差被认为是新方法校正患者摆位的残余误差的估计值。分析了 27 名早期乳腺癌患者的 145 次扫描。对基于皮肤标记的光学表面扫描和 CBCT 的患者配准的设置误差进行了相关性分析，并减少了治疗床运动校正后光学表面扫描确定的残余设置误差。光学表面成像为改善乳腺癌患者的摆位准确性提供了一种便捷的方法，而无需不必要的成像剂量。
