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在全转诊新生儿重症监护病房中减少开始和推进肠内喂养的时间。

Reducing time to initiation and advancement of enteral feeding in an all-referral neonatal intensive care unit.

机构信息

Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.

Division of Newborn Medicine, Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.

出版信息

J Perinatol. 2018 Jul;38(7):936-943. doi: 10.1038/s41372-018-0110-2. Epub 2018 May 8.

Abstract

OBJECTIVE

Decrease time to enteral feeding initiation and advancement.

STUDY DESIGN

In our all-referral neonatal intensive care unit, we developed an evidence-based guideline addressing feeding initiation and advancement. During 6 months before and 7 months after guideline implementation, we measured time to initiate feeding, time to 100 ml/kg/day of feeding, gastric residual measurement frequency, and incidence of necrotizing enterocolitis (balancing measure).

RESULT

Two hundred twenty-three infants were studied. Time from admission to feeding initiation was shorter after guideline implementation (mean 0.5 days [95% CI: 0.4-0.7] vs. 1.1 days [95% CI: 0.7-1.5], p = 0.01). Time from admission to 100 ml/kg/day feeding was also shorter (3.6 days [95% CI: 2.8-4.4] vs. 6.2 days [95% CI: 4.4-8.1], p = 0.01). After guideline implementation, routine gastric residual measurements were discontinued.

CONCLUSION

After implementation of an enteral feeding guideline, which included discontinuation of routine gastric residual assessment, we observed a faster initiation of enteral feeding and shorter time to reach 100 ml/kg/day.

摘要

目的

缩短肠内喂养起始和推进的时间。

研究设计

在我们的全转诊新生儿重症监护病房,我们制定了一项基于证据的指南,涉及喂养的起始和推进。在指南实施前 6 个月和实施后 7 个月,我们测量了开始喂养的时间、达到 100ml/kg/天喂养量的时间、胃残留测量频率以及坏死性小肠结肠炎的发生率(平衡措施)。

结果

研究了 223 名婴儿。实施指南后,从入院到开始喂养的时间更短(平均 0.5 天[95%CI:0.4-0.7] vs. 1.1 天[95%CI:0.7-1.5],p=0.01)。从入院到达到 100ml/kg/天喂养量的时间也更短(3.6 天[95%CI:2.8-4.4] vs. 6.2 天[95%CI:4.4-8.1],p=0.01)。实施指南后,停止了常规胃残留测量。

结论

在实施包括停止常规胃残留评估的肠内喂养指南后,我们观察到肠内喂养的起始更快,达到 100ml/kg/天的时间更短。

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