Johnson Blair D, O'Leary Morgan C, McBryde Muhamed, Sackett James R, Schlader Zachary J, Leddy John J
Center for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
UBMD, Department of Orthopaedics and Sports Medicine, University at Buffalo, Buffalo, New York.
Physiol Rep. 2018 May;6(9):e13694. doi: 10.14814/phy2.13694.
We tested the hypothesis that concussed college athletes (CA) have attenuated parasympathetic and sympathetic responses to face cooling (FC). Eleven symptomatic CA (age: 20 ± 2 years, 5 women) who were within 10 days of concussion diagnosis and 10 healthy controls (HC; age: 24 ± 4 years, 5 women) participated. During FC, a plastic bag filled with ice water (~0°C) was placed on the forehead, eyes, and cheeks for 3 min. Heart rate (ECG) and blood pressure (photoplethysmography) were averaged at baseline and every 60 sec during FC. High-frequency (HF) power was obtained from spectral analysis of the R-R interval. Data are presented as a change from baseline. Baseline heart rate (HC: 61 ± 12, CA: 57 ± 12 bpm; P = 0.69), mean arterial pressure (MAP) (HC: 94 ± 10, CA: 96 ± 13 mmHg; P = 0.74), and HF (HC: 2294 ± 2314, CA: 2459 ± 2058 msec ; P = 0.86) were not different between groups. Heart rate in HC decreased at 2 min (-7 ± 11 bpm; P = 0.02) but did not change in CA (P > 0.43). MAP increased at 1 min (HC: 12 ± 6, CA: 6 ± 6 mmHg), 2 min (HC: 21 ± 7, CA: 11 ± 7 mmHg), and 3 min (HC: 20 ± 6, CA: 13 ± 7 mmHg) in both groups (P < 0.01 for all) but the increase was greater at each interval in HC (P < 0.02). HF increased at 1 min (12354 ± 11489 msec ; P < 0.01) and 2 min (5832 ± 8002 msec ; P = 0.02) in HC but did not change in CA (P > 0.58). The increase in HF at 1 min was greater in HC versus CA (P < 0.01). These data indicate that symptomatic concussed patients have impaired cardiac parasympathetic and sympathetic activation.
遭受脑震荡的大学生运动员（CA）对脸部冷却（FC）的副交感神经和交感神经反应减弱。11名有症状的CA（年龄：20±2岁，5名女性）参与了研究，他们在脑震荡诊断后10天内，另有10名健康对照者（HC；年龄：24±4岁，5名女性）参与。在FC过程中，一个装满冰水（约0°C）的塑料袋被放置在前额、眼睛和脸颊上3分钟。在基线期以及FC过程中每隔60秒记录一次心率（心电图）和血压（光电容积脉搏波描记法）。高频（HF）功率通过对R-R间期的频谱分析获得。数据以相对于基线的变化表示。两组之间的基线心率（HC：61±12，CA：57±12次/分钟；P = 0.69）、平均动脉压（MAP）（HC：94±10，CA：96±13 mmHg；P = 0.74）和HF（HC：2294±2314，CA：2459±20
