Department of Rehabilitation Science, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, USA.
UBMD Orthopaedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA.
Physiol Rep. 2024 Nov;12(21):e70114. doi: 10.14814/phy2.70114.
Sport-related concussion (SRC) is associated with cardiovascular autonomic nervous system (ANS) dysfunction. This study examines resting cardiovascular ANS activity in adolescents with SRC compared to controls early post-injury and after clinical recovery, analyzing its correlation with symptom severity and recovery outcomes. Cardiovascular ANS function was evaluated using heart rate variability (HRV), systolic blood pressure variability (SBPV) and baroreflex sensitivity (BRS). Symptoms were assessed via the Post-Concussion Symptom Scale, and recovery outcomes were categorized by recovery duration. Following acute SRC, no significant differences in HRV, SBPV or BRS were found between SRC and control groups, nor between those with delayed or normal recovery. Post-recovery, SRC participants had higher low frequency (LF) SBPV than controls and their initial assessment. When concussed participants were symptomatic, LF SBPV correlated directly with overall, cognitive, and fatigue symptom severity, while high frequency (HF) HRV inversely correlated with affective symptoms (Spearman's rho: 0.4-0.6). Resting cardiovascular ANS function remains unchanged in adolescent athletes acutely after SRC, suggesting it has limited diagnostic and prognostic potential. Although some correlations between individual symptom domains and ANS activity were observed, they were not significantly different from asymptomatic controls, limiting the ability to interpret these findings.
运动相关性脑震荡 (SRC) 与心血管自主神经系统 (ANS) 功能障碍有关。本研究比较了 SRC 青少年在受伤后早期和临床康复后的静息心血管 ANS 活动，分析了其与症状严重程度和康复结果的相关性。使用心率变异性 (HRV)、收缩压变异性 (SBPV) 和压力反射敏感性 (BRS) 评估心血管 ANS 功能。通过脑震荡后症状量表评估症状，根据恢复持续时间对恢复结果进行分类。在急性 SRC 后，SRC 组和对照组之间、恢复延迟或正常的组之间，HRV、SBPV 或 BRS 均无显著差异。恢复后，SRC 参与者的 LF SBPV 高于对照组和他们的初始评估。当患有脑震荡的参与者出现症状时，LF SBPV 与整体、认知和疲劳症状的严重程度直接相关，而高频 (HF) HRV 与情感症状呈负相关 (Spearman's rho：0.4-0.6)。青少年运动员在 SRC 后急性发作时，心血管自主神经功能保持不变，表明其具有有限的诊断和预后潜力。尽管观察到个别症状域和 ANS 活动之间存在一些相关性，但与无症状对照组相比没有显著差异，限制了对这些发现的解释能力。
