Lehot J J, Carre R, Cottet-Emard J M, Guidollet J, Estavove S
Département d'Anesthésie-Réanimation, Hôpital cardiovasculaire Louis Pradel, Lyon.
Presse Med. 1988 Nov 12;17(40):2121-4.
The difference between oxygen consumption during spontaneous and controlled ventilation represents the oxygen cost of breathing. Swan-Ganz catheters enable oxygen consumption to be calculated as the product of cardiac index by arteriovenous oxygen concentration. This method was used in 25 patients on the day after anaesthesia and mitral valve replacement to predict the success of weaning from mechanical ventilation. Four patients could not be weaned: one for pulmonary reasons, one for neurological reasons and two because of their cardiac status. Whether weaning was successful or not, oxygen consumption did not change significantly during spontaneous respiration; concomitantly lactacidaemia remained stable. Two patients had an oxygen consumption below the physiological threshold (115 ml.min-1.m-2): one could be weaned, but not the other. Haemodynamic parameters did not change significantly during weaning. Thus, measurement of oxygen consumption through a Swan-Ganz catheter does not predict the success of weaning after mitral valve replacement, but the catheter can diagnose a low cardiac output needing treatment before weaning.
自主呼吸与控制通气时的耗氧量差值代表呼吸的氧耗。 Swan-Ganz导管可通过心指数与动静脉氧浓度的乘积来计算耗氧量。该方法应用于25例麻醉及二尖瓣置换术后次日的患者,以预测机械通气撤机的成功率。4例患者未能撤机:1例因肺部原因,1例因神经学原因,2例因心脏状况。无论撤机是否成功,自主呼吸期间耗氧量均无显著变化;同时,血乳酸水平保持稳定。2例患者的耗氧量低于生理阈值(115 ml·min⁻¹·m⁻²):1例能够撤机,另1例则不能。撤机过程中血流动力学参数无显著变化。因此,通过Swan-Ganz导管测量耗氧量并不能预测二尖瓣置换术后撤机的成功率,但该导管可在撤机前诊断出需要治疗的低心排血量情况。