Nanostructured Molecular Systems and Materials group, Organic Chemistry Department, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Theoretical Chemistry and ACMM, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Chemistry. 2018 Aug 14;24(46):11983-11991. doi: 10.1002/chem.201801704. Epub 2018 Jul 2.
Supramolecular ring-versus-chain equilibria are ubiquitous in biological and synthetic systems. Understanding the factors that decide whether a system will fall on one side or the other is crucial to the control of molecular self-assembly. This work reports results with two kinds of dinucleoside monomers, in which the balance between closed cycles and open polymers is found to depend on subtle factors that rule conformational equilibria, such as steric hindrance, intramolecular interactions, or π-conjugation pathways.
超分子环-链平衡在生物和合成系统中无处不在。了解决定系统偏向于哪一边的因素对于控制分子自组装至关重要。这项工作报道了两种二核苷酸单体的结果，其中发现封闭环和开链聚合物之间的平衡取决于控制构象平衡的细微因素，如空间位阻、分子内相互作用或π-共轭途径。
