视路和丘脑的小儿胶质瘤
Pediatric Glioma at the Optic Pathway and Thalamus.
作者信息
Park Eun Suk, Park Jun Bum, Ra Young-Shin
机构信息
Department of Neurosurgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
出版信息
J Korean Neurosurg Soc. 2018 May;61(3):352-362. doi: 10.3340/jkns.2018.0040. Epub 2018 May 1.
Gliomas are the most common pediatric tumors of the central nervous system. In this review, we discuss the clinical features, treatment paradigms, and evolving concepts related to two types of pediatric gliomas affecting two main locations: the optic pathway and thalamus. In particular, we discuss recently revised pathologic classification, which adopting molecular parameter. We believe that our review contribute to the readers' better understanding of pediatric glioma because pediatric glioma differs in many ways from adult glioma according to the newest advances in molecular characterization of this tumor. A better understanding of current and evolving issues in pediatric glioma is needed to ensure effective management decision.
神经胶质瘤是中枢神经系统最常见的儿科肿瘤。在本综述中，我们讨论了与影响两个主要部位（视路和丘脑）的两种儿科神经胶质瘤相关的临床特征、治疗模式及不断演变的概念。特别是，我们讨论了最近采用分子参数修订的病理分类。我们相信，我们的综述有助于读者更好地了解儿科神经胶质瘤，因为根据该肿瘤分子特征的最新进展，儿科神经胶质瘤在许多方面与成人神经胶质瘤不同。为确保做出有效的管理决策，需要更好地了解儿科神经胶质瘤当前及不断演变的问题。
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