针对试图戒烟的女性产前和产后抑郁的体育活动：随机对照试验。
Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial.
作者信息
Daley Amanda, Riaz Muhammad, Lewis Sarah, Aveyard Paul, Coleman Tim, Manyonda Isaac, West Robert, Lewis Beth, Marcus Bess, Taylor Adrian, Ibison Judith, Kent Andrew, Ussher Michael
机构信息
Sport, Exercise and Health Sciences, Loughborough University, Epinal Way, Loughborough, Leicestershire, LE11 3TU, UK.
Population Health Research Institute, University of Leicester, University Road, Leicester, LE1 7RH, UK.
出版信息
BMC Pregnancy Childbirth. 2018 May 10;18(1):156. doi: 10.1186/s12884-018-1784-3.
BACKGROUND
Antenatal depression is associated with harmful consequences for both the mother and child. One intervention that might be effective is participation in regular physical activity although data on this question in pregnant smokers is currently lacking.
METHODS
Women were randomised to six-weekly sessions of smoking cessation behavioural-support, or to the same support plus 14 sessions combining treadmill exercise and physical activity consultations.
RESULTS
Among 784 participants (mean gestation 16-weeks), EPDS was significantly higher in the physical activity group versus usual care at end-of-pregnancy (mean group difference (95% confidence intervals (CIs)): 0.95 (0.08 to 1.83). There was no significant difference at six-months postpartum.
CONCLUSION
A pragmatic intervention to increase physical activity in pregnant smokers did not prevent depression at end-of-pregnancy or at six-months postpartum. More effective physical activity interventions are needed in this population.
TRIAL REGISTRATION
Current Controlled Trials ISRCTN48600346 . The trial was prospectively registered on 21/07/2008.
背景
产前抑郁对母亲和孩子都会产生有害影响。一种可能有效的干预措施是定期进行体育锻炼，不过目前缺乏关于怀孕吸烟者这方面问题的数据。
方法
将女性随机分为两组，一组接受为期六周的戒烟行为支持治疗，另一组在接受相同支持治疗的基础上，再参加14节结合跑步机锻炼和体育活动咨询的课程。
结果
在784名参与者（平均孕周16周）中，孕期结束时，体育活动组的爱丁堡产后抑郁量表（EPDS）得分显著高于常规护理组（组间平均差异（95%置信区间）：0.95（0.08至1.83））。产后六个月时两组无显著差异。
结论
一项旨在增加怀孕吸烟者体育活动的实用干预措施，未能预防孕期结束时或产后六个月的抑郁。该人群需要更有效的体育活动干预措施。
试验注册
当前对照试验ISRCTN48600346。该试验于2008年7月21日进行前瞻性注册。
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