Department of Epidemiology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, 04180 Košice, Slovakia.
1st Department of Internal Medicine, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, 04011 Košice, Slovakia.
Int J Environ Res Public Health. 2018 May 3;15(5):904. doi: 10.3390/ijerph15050904.
Hepatitis E infection is one of the most frequent causes of acute hepatitis in the world. Currently five human genotypes with different geographical distributions and distinct epidemiologic patterns are identified. In Slovakia, only rare cases of hepatitis E have been reported in past years. Because the most important risk factors associated with HEV infection include consumption of contaminated pork meat and poor hygienic standards, the aim of the study was to evaluate the prevalence of anti-HEV total antibodies and the main risk factors for HEV in the population living in separated and segregated Roma settlements ( = 195), which represent places with increased risk of infection in Slovakia and to compare it with the prevalence in the general population ( = 69). Of 264 respondents included in the study, 47 (17.8%) showed positivity for anti-HEV antibodies, 42 of whom were Roma (21.5%, = 195) and 5 (7.2%, = 69) non-Roma. The population living in Roma settlements lives in poorer conditions and are at higher risk of HEV in comparison to the general population. However, differences in living conditions within the settlements do not contributed to lower risk of HEV antibody prevalence between Roma living in settlements.
戊型肝炎感染是世界范围内导致急性肝炎的最常见原因之一。目前已鉴定出五种具有不同地理分布和不同流行病学模式的人类基因型。在斯洛伐克,过去几年仅报告了少数戊型肝炎病例。由于与 HEV 感染相关的最重要的危险因素包括食用受污染的猪肉和卫生条件差,因此本研究的目的是评估生活在隔离的罗姆人定居点(= 195)的人群中抗-HEV 总抗体的流行情况以及 HEV 的主要危险因素,并将其与普通人群(= 69)的流行情况进行比较。在纳入研究的 264 名受访者中,有 47 人(17.8%)抗-HEV 抗体呈阳性,其中 42 人是罗姆人(21.5%,= 195),5 人是非罗姆人(7.2%,= 69)。与普通人群相比,生活在罗姆人定居点的人群生活条件较差,感染 HEV 的风险更高。然而,定居点内生活条件的差异并没有降低定居点内罗姆人抗-HEV 抗体流行率的风险。