Section of Vascular Surgery, University of Michigan Medical School, Ann Arbor, Mich.
Section of Vascular Surgery, University of Michigan Medical School, Ann Arbor, Mich.
J Vasc Surg Venous Lymphat Disord. 2018 Jul;6(4):464-470. doi: 10.1016/j.jvsv.2018.02.008. Epub 2018 May 8.
Whereas chronic venous insufficiency and varicose veins (VVs) are a universally recognized problem, they are frequently underappreciated as major contributors to long-term morbidity in the elderly despite the increasing prevalence with age. Previous studies have demonstrated that chronic venous insufficiency and VV treatments in patients ≥65 years old yield an overall benefit; however, there have been few data as to whether octogenarians are undergoing these procedures and with what success. As such, our objectives were to investigate the procedures selected, to examine clinical outcomes after VV procedures in elderly patients ≥80 years old, and to explore complication rates (both systemic and leg specific) after VV procedures in patients ≥80 years old.
We performed a retrospective review using the Vascular Quality Initiative Varicose Vein Registry of all VV procedures performed for ≥C2 disease from January 2015 to February 2017. We divided all procedures into three age groups: patients <65 years, patients ≥65 to 79 years, and patients ≥80 years. Statistical testing included χ test for categorical variables and Student t-test for continuous variables. Two comparisons were performed: first, comparing patients <65 years old with patients ≥65 to 79 years old; and second, comparing patients ≥65 to 79 years old with patients ≥80 years old.
There were a total of 12,262 procedures performed, with 8608 procedures in the patients <65 years, 3226 in patients 65 to 79 years, and 428 procedures in patients ≥80 years. A total of 22,050 veins were treated during the 12,262 procedures. Almost half of procedures (46.51%; n = 5703) had only one vein treated during a single procedure. Between age groups, the percentage of one vein treated increased as the patient's age increased, ranging from 45.39% (n = 3875) for patients <65 years to 48.55% (n = 1555) for patients between 65 and 79 years and 64.08% (n = 273) for patients ≥80 years. Patients in the group ≥80 years had an overall lower average body mass index and were more likely to be receiving anticoagulation and to undergo truncal procedures alone compared with the other groups. The group ≥80 years had a significant improvement in both Venous Clinical Severity Score (4.37 ± 4.16; P < .001) and patient-reported outcomes (8.79 ± 7.27; P < .001) from before to after the procedure. Overall complications were low in all age groups. The octogenarians had no higher risk of systemic complications.
Vascular specialists are performing VV procedures in octogenarians and are more likely to perform truncal only therapy. In addition, octogenarians have statistically significant improvement of Venous Clinical Severity Score and patient-reported outcomes with a low risk of complications despite more advanced venous disease at presentation.
尽管慢性静脉功能不全和静脉曲张(VV)是一个普遍公认的问题,但随着年龄的增长,它们在老年人中的发病率越来越高,尽管它们是长期发病的主要原因,但仍经常被低估。以前的研究已经表明,≥65 岁的慢性静脉功能不全和 VV 治疗总体上有益;然而,关于 80 岁以上的老年人是否接受这些治疗以及治疗效果如何,数据很少。因此,我们的目的是调查选择的治疗方法,检查≥80 岁的老年患者 VV 手术后的临床结果,并探讨≥80 岁的患者 VV 手术后的并发症发生率(全身性和腿部特定性)。
我们使用血管质量倡议静脉曲张登记处的回顾性研究,对 2015 年 1 月至 2017 年 2 月期间≥C2 疾病的所有 VV 手术进行了回顾。我们将所有手术分为三组年龄组:<65 岁、≥65 至 79 岁和≥80 岁。统计检验包括分类变量的卡方检验和连续变量的学生 t 检验。进行了两次比较:第一次比较<65 岁的患者与≥65 至 79 岁的患者;第二次比较≥65 至 79 岁的患者与≥80 岁的患者。
共有 12262 例手术,<65 岁的患者 8608 例,65 至 79 岁的患者 3226 例,≥80 岁的患者 428 例。在 12262 例手术中,共治疗了 22050 条静脉。近一半的手术(46.51%;n=5703)在单次手术中仅治疗一条静脉。随着患者年龄的增长,各年龄组中仅治疗一条静脉的比例增加,从<65 岁的患者(45.39%;n=3875)到 65 至 79 岁的患者(48.55%;n=1555)和≥80 岁的患者(64.08%;n=273)。≥80 岁的患者的平均体重指数总体较低,更有可能接受抗凝治疗,并单独进行干骺端手术。≥80 岁的患者在静脉临床严重程度评分(4.37±4.16;P<0.001)和患者报告的结果(8.79±7.27;P<0.001)方面均有显著改善。所有年龄组的总体并发症发生率均较低。≥80 岁的患者没有更高的全身性并发症风险。
血管专家正在为 80 岁以上的患者进行 VV 手术,并且更有可能进行干骺端治疗。此外,尽管在发病时存在更严重的静脉疾病,但≥80 岁的患者的静脉临床严重程度评分和患者报告的结果均有统计学意义的改善,且并发症风险较低。