上肢人群中患者报告结果测量信息系统（PROMIS）工具和上肢功能障碍与残疾问卷（qDASH）的反应度。
The responsiveness of the PROMIS instruments and the qDASH in an upper extremity population.
作者信息
Hung Man, Saltzman Charles L, Greene Tom, Voss Maren W, Bounsanga Jerry, Gu Yushan, Wang Angela A, Hutchinson Douglas, Tyser Andrew R
机构信息
1Department of Orthopaedic Surgery Operations, University of Utah, School of Medicine, 590 Wakara Way, Salt Lake City, UT 84108 USA.
2Division of Public Health, University of Utah, School of Medicine, 375 Chipeta Way Ste. A, Salt Lake City, 84108 USA.
出版信息
J Patient Rep Outcomes. 2017;1(1):12. doi: 10.1186/s41687-017-0019-0. Epub 2017 Nov 28.
BACKGROUND
This study evaluated the responsiveness of several PROMIS patient-reported outcome measures in patients with hand and upper extremity disorders and provided comparisons with the qDASH instrument.
METHODS
The PROMIS Upper Extremity computer adaptive test (UE CAT) v1.2, the PROMIS Physical Function (PF) CAT v1.2, the PROMIS Pain Interference (PI) CAT v1.1 and the qDASH were administered to patients presenting to an orthopaedic hand clinic during the years 2014-2016, along with anchor questions. The responsiveness of these instruments was assessed using anchor based methods. Changes in functional outcomes were evaluated by paired-sample t-test, effect size, and standardized response mean.
RESULTS
There were a total of 255 patients (131 females and 124 males) with an average age of 50.75 years (SD = 15.84) included in our study. Based on the change and no change scores, there were three instances (PI at 3 months, PI >3 months, and qDASH >3 months follow-ups) where scores differed between those experiencing clinically meaningful change versus no clinically meaningful change. Effect sizes for the responsiveness of all instruments were large and ranged from 0.80-1.48. All four instruments demonstrated high responsiveness, with a standardized response mean ranging from 1.05 to 1.63.
CONCLUSION
The PROMIS UE CAT, PF CAT, PI CAT, and qDASH are responsive to patient-reported functional change in the hand and upper extremity patient population.
背景
本研究评估了几种患者报告结局测量信息系统（PROMIS）在手部和上肢疾病患者中的反应度，并与上肢功能障碍问卷（qDASH）进行了比较。
方法
在2014年至2016年期间，对到骨科手部诊所就诊的患者进行了PROMIS上肢计算机自适应测试（UE CAT）v1.2、PROMIS身体功能（PF）CAT v1.2、PROMIS疼痛干扰（PI）CAT v1.1和qDASH评估，并设置了对照问题。使用基于对照的方法评估这些工具的反应度。通过配对样本t检验、效应量和标准化反应均值评估功能结局的变化。
结果
本研究共纳入255例患者（131例女性和124例男性），平均年龄50.75岁（标准差=15.84）。根据变化和未变化评分，在3个月时的PI、3个月以上的PI以及3个月以上随访的qDASH这三种情况下，经历临床有意义变化的患者与未经历临床有意义变化的患者之间得分存在差异。所有工具反应度的效应量都很大，范围在0.80至1.48之间。所有四种工具均显示出高反应度，标准化反应均值范围为1.05至1.63。
结论
PROMIS UE CAT、PF CAT、PI CAT和qDASH对患者报告的手部和上肢患者群体功能变化有反应。
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