Castleberry Todd J, England Dwiesha L, Fylstra Bretta L, Stevens Phillip M, Todd Amy E, Mandacina Stephen A, Wurdeman Shane R
Hanger Institute for Clinical Research and Education, 10910 Domain Dr., Ste. 300, Austin, TX, 78758, USA.
Division of Physical Medicine and Rehabilitation, University of Utah Health, Salt Lake City, UT, USA.
J Patient Rep Outcomes. 2025 Feb 10;9(1):17. doi: 10.1186/s41687-025-00843-y.
Upper extremity physical function is an essential health domain in the rehabilitation care for patients with upper limb amputation or absence. The PROMIS-9 UE Physical Function short form is a recently established instrument designed for individuals with upper limb amputation or absence. The instrument's responsiveness to changes after receiving a prosthesis has not been investigated. The current study aimed to evaluate the ability of the PROMIS-9 UE to detect changes in bimanual (two-handed) functional capacity after patients' receipt of a prosthesis.
A retrospective chart review was conducted on the longitudinal PROMIS-9 UE outcome measure scores completed between April 2016 and February 2024. Participants included individuals with an outcome collected before and after prosthesis receipt.
The final sample size included 124 individuals (91 male, 33 female; 43.4 ± 15.0 years old, 34.4 ± 103.0 months since amputation, and 62.9% injury etiology). Analyses found significant improvement across all patients in the PROMIS-9 UE scores from baseline to post prosthesis intervention (baseline: 25.3 ± 8.6, post: 29.5 ± 9.6; p < 0.001). The PROMIS-9 UE demonstrated a moderate responsiveness (Standardized Response Mean = 0.6) to prosthetic intervention. This was a directional change consistent with subjective patient reports of increased functionality. Furthermore, findings from the linear mixed model demonstrated significant responsiveness for the PROMIS-9 UE instrument to detect post-intervention changes after controlling for potential confounding effects (p < 0.001).
These findings suggest the PROMIS-9 UE Physical Function instrument demonstrates moderate clinical utility in capturing patient progress following upper limb prosthesis intervention.
上肢身体功能是上肢截肢或缺失患者康复护理中的一个重要健康领域。PROMIS-9上肢身体功能简表是最近为上肢截肢或缺失个体设计的一种工具。该工具对接受假肢后变化的反应性尚未得到研究。本研究旨在评估PROMIS-9上肢简表检测患者接受假肢后双手(双手)功能能力变化的能力。
对2016年4月至2024年2月期间完成的纵向PROMIS-9上肢结局测量分数进行回顾性图表审查。参与者包括在接受假肢前后收集结局的个体。
最终样本量包括124名个体(91名男性,33名女性;43.4±15.0岁,截肢后34.4±103.0个月,损伤病因占62.9%)。分析发现,从基线到假肢干预后,所有患者的PROMIS-9上肢分数均有显著改善(基线:25.3±8.6,干预后:29.5±9.6;p<0.001)。PROMIS-9上肢简表对假肢干预表现出中等反应性(标准化反应均值=0.6)。这是一个与患者关于功能增加的主观报告一致的方向性变化。此外,线性混合模型的结果表明,在控制潜在混杂效应后,PROMIS-9上肢简表能够显著检测干预后的变化(p<0.001)。
这些发现表明,PROMIS-9上肢身体功能工具在捕捉上肢假肢干预后患者的进展方面具有中等临床效用。