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[不同程度皮肤点刺试验对变应性鼻炎皮下免疫治疗短期疗效的影响]

[Influence of different levels of skin pricking test on the short-term efficacy of subcutaneous immunotherapy in allergic rhinitis].

作者信息

Liu Yan, Lin Yu Qiang, Geng Cong Li, Yuan Xiao Pei, Wang Min, Xing Zhi Min

机构信息

Department of Otorhinolaryngology,Peking University People's Hospital Beijing,100044,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 20;32(2):102-105. doi: 10.13201/j.issn.1001-1781.2018.02.006.

Abstract

To explore the effect of different levels of skin pricking test on short-term efficacy of subcutaneous immunotherapy with allergic rhinitis.Thirty-one AR patients were included in our study.All the patients had received subcutaneous immunotherapy for 1 year.According to the levels of SPT the patients were divided into 3 groups(grade 2,10 persons;grade 3,10 persons and grade 4,11 persons).Of all the patients,the nasal symptoms visual analogue scale(VAS)score,medication score and rhinoconjunctivitis quality of life questionnaire(RQLQ)were investigated both before and after receiving 1 year subcutaneous immunotherapy.The total effective rate of VAS score,RQLQ score and medication score was 61.30%,58.06% and 64.52% respectively,but there was no statistical difference among the 3 groups after 1 year subcutaneous immunotherapy(P=0.573,0.136,0.699,>0.05).This study confirms the short efficacy of subcutaneous immunotherapy in AR patients with different levels of SPT.But the level of SPT was not an objective index for shortterm efficacy of subcutaneous immunotherapy of AR.

摘要

探讨不同皮肤点刺试验(SPT)水平对过敏性鼻炎皮下免疫治疗短期疗效的影响。本研究纳入了31例变应性鼻炎(AR)患者。所有患者均接受了1年的皮下免疫治疗。根据SPT水平将患者分为3组(2级,10人;3级,10人;4级,11人)。对所有患者在接受1年皮下免疫治疗前后均进行鼻症状视觉模拟量表(VAS)评分、用药评分及鼻结膜炎生活质量问卷(RQLQ)调查。VAS评分、RQLQ评分及用药评分的总有效率分别为61.30%、58.06%和64.52%,但皮下免疫治疗1年后3组间差异无统计学意义(P = 0.573、0.136、0.699,>0.05)。本研究证实了皮下免疫治疗对不同SPT水平的AR患者有短期疗效。但SPT水平并非AR皮下免疫治疗短期疗效的客观指标。

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