Guo J F, Liu P, Wu H Q, Lin L L, Liu Z, Xiong B B
Department of Otolaryngology, the People's Hospital of Zhuhai, Jinan University, Zhuhai, 519000, China.
Department of Psychiatry, the People's Hospital of Zhuhai, Jinan University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 May 5;30(9):712-714. doi: 10.13201/j.issn.1001-1781.2016.09.010.
To study the effect of specific immunotherapy on the psychological health level and quality of life in patients with allergic rhinitis(AR).Selected 97 cases diagnosed as moderate to severe persistent AR patients, were treated with specific immunotherapy for one year. All patients received the evaluation with symptom check list 90(SCL-90) and rhinoconjunctivitis quality of life questionnaire(RQLQ) before specific immunotherapy, six, and 12 months after specific immunotherapy.The total scores, scores of somatization, obsessive, anxiety, depression and phobia in SCL-90 of AR patients after 12 months treatment were significantly lower than that before treatment（ < 0.05）. Total score of quality of life and subitem score in RQLQ of AR patients after 12 months treatment were obviously lower than that before treatment ( < 0.05）.Specific immunotherapy can effectively alleviate the clinical symptoms and improve psychological health level and quality of life of AR patients.
研究特异性免疫疗法对变应性鼻炎（AR）患者心理健康水平及生活质量的影响。选取97例诊断为中重度持续性AR的患者，给予特异性免疫疗法治疗1年。所有患者在特异性免疫疗法前、治疗6个月及12个月后均接受症状自评量表90（SCL-90）和鼻结膜炎生活质量问卷（RQLQ）评估。治疗12个月后，AR患者SCL-90中躯体化、强迫、焦虑、抑郁及恐惧得分及总分均显著低于治疗前（P<0.05）。治疗12个月后，AR患者RQLQ生活质量总分及各分项得分均明显低于治疗前（P<0.05）。特异性免疫疗法可有效缓解AR患者的临床症状，提高其心理健康水平及生活质量。
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