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[暴露于 +5Gz 加速度的大鼠心房心肌细胞的超微结构分析]

[Ultrastructural analysis of atrial cardiomyocytes of rats exposed to acceleration +5Gz].

作者信息

Artemian N A, Barinian S B, Oganesian S S, Shperling I D

出版信息

Kosm Biol Aviakosm Med. 1988 Sep-Oct;22(5):60-4.

PMID:2976103
Abstract

Ultrastructural changes in atrial cardiomyocytes of rats chronically exposed to +5 Gz were investigated. Immediately after exposure most cardiomyocytes showed hypertrophic and hyperplastic changes in practically all cell organelles. During a month-long recovery destructive changes that seemed to reflect hypertrophy regression did not return to norm. The above observations concerning changes in the system of atrial hormones together with pertinent data in the literature suggest that a factor produced by the system may be involved in the complex mechanism of acceleration-induced effects on the animal body.

摘要

研究了长期暴露于+5 Gz 的大鼠心房心肌细胞的超微结构变化。暴露后立即观察到,几乎所有细胞器中的大多数心肌细胞都出现了肥大和增生性变化。在长达一个月的恢复期间,看似反映肥大消退的破坏性变化并未恢复正常。上述关于心房激素系统变化的观察结果以及文献中的相关数据表明,该系统产生的一种因子可能参与了加速度对动物机体影响的复杂机制。

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