使用diArk识别已测序的真核生物基因组和转录组。

Identifying Sequenced Eukaryotic Genomes and Transcriptomes with diArk.

作者信息

Kollmar Martin, Simm Dominic

机构信息

Group Systems Biology of Motor Proteins, Department of NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.

Theoretical Computer Science and Algorithmic Methods, Institute of Computer Science, Georg-August-University, Göttingen, Germany.

出版信息

Methods Mol Biol. 2018;1757:1-19. doi: 10.1007/978-1-4939-7737-6_1.

DOI:10.1007/978-1-4939-7737-6_1

PMID:29761453

Abstract

The diArk Eukaryotic Genome Database is a manually curated and updated repository of available eukaryotic genome and transcriptome assemblies. diArk is a key resource for researchers interested in comparative eukaryotic genomics, and the entry point to browsing sequenced eukaryotes in general and to find the most closely related species to the own organism of interest in particular. The exponentially increasing number of sequenced species demands sophisticated search and data presentation tools. In this chapter we describe how to navigate the diArk database keeping a first-time user in mind.

摘要

diArk真核生物基因组数据库是一个经过人工整理和更新的、存储可用真核生物基因组和转录组组装数据的资源库。diArk是对比较真核生物基因组学感兴趣的研究人员的关键资源，也是浏览一般测序真核生物以及特别查找与感兴趣的自身生物体关系最密切物种的切入点。测序物种数量呈指数级增长，这就需要复杂的搜索和数据呈现工具。在本章中，我们将介绍如何在考虑首次用户的情况下浏览diArk数据库。