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使用寄生虫基因组数据库(WormBase ParaSite):一个用于探索蠕虫基因组数据的集成平台。

Using WormBase ParaSite: An Integrated Platform for Exploring Helminth Genomic Data.

作者信息

Bolt Bruce J, Rodgers Faye H, Shafie Myriam, Kersey Paul J, Berriman Matthew, Howe Kevin L

机构信息

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK.

Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.

出版信息

Methods Mol Biol. 2018;1757:471-491. doi: 10.1007/978-1-4939-7737-6_15.

Abstract

WormBase ParaSite ( parasite.wormbase.org ) is a comprehensive resource for the genomes of parasitic nematodes and flatworms (helminths). It currently includes genomic data for over 100 helminth species, adding value by way of consistent functional annotation, gene comparative analysis and gene expression analysis. We provide several ways of exploring the data including a choice of genome browsers, genome and gene summary pages, text and sequence searching, a query wizard, bulk downloads, and programmatic interfaces. WormBase ParaSite is released three to six times per year, and is developed in collaboration with WormBase ( www.wormbase.org ) and Ensembl Genomes ( www.ensemblgenomes.org ).

摘要

WormBase ParaSite(parasite.wormbase.org)是寄生线虫和扁虫(蠕虫)基因组的综合资源库。它目前包含100多种蠕虫物种的基因组数据,通过一致的功能注释、基因比较分析和基因表达分析增加其价值。我们提供多种探索数据的方式,包括多种基因组浏览器选择、基因组和基因摘要页面、文本和序列搜索、查询向导、批量下载以及编程接口。WormBase ParaSite每年发布三到六次,是与WormBase(www.wormbase.org)和Ensembl Genomes(www.ensemblgenomes.org)合作开发的。

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