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[用于强迫振荡技术的伪随机输入信号的优化]

[Optimization of the pseudorandom input signals used for the forced oscillation technique].

作者信息

Liu Xiaoli, Zhang Nan, Liang Hong, Zhang Zhengbo, Li Deyu, Wang Weidong

机构信息

School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, P.R.China.

Department of Biomedical Engineering, Chinese PLA General Hospital, Beijing 100853, P.R.China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2017 Oct 1;34(5):660-666. doi: 10.7507/1001-5515.201607064.

Abstract

The forced oscillation technique (FOT) is an active pulmonary function measurement technique that was applied to identify the mechanical properties of the respiratory system using external excitation signals. FOT commonly includes single frequency sine, pseudorandom and periodic impulse excitation signals. Aiming at preventing the time-domain amplitude overshoot that might exist in the acquisition of combined multi sinusoidal pseudorandom signals, this paper studied the phase optimization of pseudorandom signals. We tried two methods including the random phase combination and time-frequency domain swapping algorithm to solve this problem, and used the crest factor to estimate the effect of optimization. Furthermore, in order to make the pseudorandom signals met the requirement of the respiratory system identification in 4-40 Hz, we compensated the input signals' amplitudes at the low frequency band (4-18 Hz) according to the frequency-response curve of the oscillation unit. Resuts showed that time-frequency domain swapping algorithm could effectively optimize the phase combination of pseudorandom signals. Moreover, when the amplitudes at low frequencies were compensated, the expected stimulus signals which met the performance requirements were obtained eventually.

摘要

强迫振荡技术(FOT)是一种主动肺功能测量技术,该技术通过外部激励信号来识别呼吸系统的力学特性。FOT通常包括单频正弦、伪随机和周期性脉冲激励信号。针对在采集组合多正弦伪随机信号时可能存在的时域幅度过冲问题,本文研究了伪随机信号的相位优化。我们尝试了随机相位组合和时频域交换算法两种方法来解决该问题,并使用波峰因数来评估优化效果。此外,为使伪随机信号满足4 - 40Hz范围内呼吸系统识别的要求,我们根据振荡单元的频率响应曲线对低频段(4 - 18Hz)的输入信号幅度进行了补偿。结果表明,时频域交换算法能够有效优化伪随机信号的相位组合。此外,对低频幅度进行补偿后,最终获得了满足性能要求的预期刺激信号。

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本文引用的文献

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Usefulness of Colored 3D Imaging of Respiratory Impedance in Asthma.彩色 3D 呼吸阻抗成像在哮喘中的应用。
Allergy Asthma Immunol Res. 2013 Sep;5(5):322-8. doi: 10.4168/aair.2013.5.5.322. Epub 2013 Jul 24.
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Oscillation mechanics of lungs and chest in man.人体肺部和胸部的振荡力学
J Appl Physiol. 1956 May;8(6):587-94. doi: 10.1152/jappl.1956.8.6.587.
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Influence of signal processing on estimation of respiratory impedance.信号处理对呼吸阻抗估计的影响。
J Appl Physiol (1985). 1993 Jan;74(1):215-23. doi: 10.1152/jappl.1993.74.1.215.

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