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牙槽嵴保存中的皮瓣管理:系统评价与Meta分析

Flap Management in Alveolar Ridge Preservation: A Systematic Review and Meta-Analysis.

作者信息

Lee Jungwon, Lee Jun-Beom, Koo Ki-Tae, Seol Yang-Jo, Lee Yong-Moo

出版信息

Int J Oral Maxillofac Implants. 2018 May/Jun;33(3):613-621. doi: 10.11607/jomi.6368.

Abstract

PURPOSE

This systematic review aimed to identify the effects of certain flap management procedures on ridge preservation on the basis of existing literature.

MATERIALS AND METHODS

Electronic (MEDLINE, EMBASE, and Cochrane Central Register of controlled trials) and manual searches of the literature were conducted until February 2017. Randomized controlled trials (RCTs), controlled clinical trials (CCTs), and prospective cohort studies that involved at least 10 subjects were eligible for this systematic review. To evaluate the beneficial effects of flap management on ridge preservation, changes in the bone width, bone height, and keratinized gingiva width were calculated using a random effects model.

RESULTS

Eleven studies (nine RCTs and two CCTs) were included in this review. No statistically significant differences in bone width and height changes were identified between the flapped and flapless ridge preservation techniques and between the free gingival graft and flapless ridge preservation techniques. A statistically significant shrinkage in keratinized gingiva width was noted with flapped ridge preservation compared with flapless ridge preservation (weighted mean differences, -3.21 mm; 95% confidence interval, -4.10 to -2.33; P < .00001; heterogeneity, 51%; χ, 0.15).

CONCLUSION

Within the limitations, this review reveals that flapless ridge preservation was more effective in preserving bone width, bone height, and keratinized gingiva width. To present pertinent evidence regarding which flap management should be recommended for ridge preservation, more controlled and high-quality studies are warranted.

摘要

目的

本系统评价旨在根据现有文献确定某些瓣处理程序对牙槽嵴保存的影响。

材料与方法

截至2017年2月,进行了电子检索(MEDLINE、EMBASE和Cochrane对照试验中央注册库)和手动文献检索。纳入至少10名受试者的随机对照试验(RCT)、对照临床试验(CCT)和前瞻性队列研究进行本系统评价。为评估瓣处理对牙槽嵴保存的有益效果,采用随机效应模型计算骨宽度、骨高度和角化龈宽度的变化。

结果

本评价纳入了11项研究(9项RCT和2项CCT)。在翻瓣与不翻瓣牙槽嵴保存技术之间以及游离龈移植与不翻瓣牙槽嵴保存技术之间,未发现骨宽度和高度变化有统计学显著差异。与不翻瓣牙槽嵴保存相比,翻瓣牙槽嵴保存时角化龈宽度有统计学显著缩小(加权平均差,-3.21mm;95%置信区间,-4.10至-2.33;P<.00001;异质性,51%;χ²,0.15)。

结论

在局限性范围内,本评价显示不翻瓣牙槽嵴保存在保存骨宽度、骨高度和角化龈宽度方面更有效。为提供关于应推荐哪种瓣处理用于牙槽嵴保存的相关证据,需要更多对照的高质量研究。

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