Institute of Pathology of the University of Hamburg, Martinistraße 52, UKE, 20246, Hamburg, Germany.
Institute of Pathology, Städtisches Klinikum Karlsruhe, 76042, Karlsruhe, Germany.
Endocr Pathol. 2018 Sep;29(3):294-298. doi: 10.1007/s12022-018-9531-x.
A 67-year-old man was adrenalectomized due to a tumor measuring 100 mm. Specimens revealed an inflammation with slight fibrosis and moderate infiltrates of lymphocytes and plasmacytes with immunoreactivity for IgG and IgG4 resulting in the diagnosis of an active IgG4-associated adrenalitis. To our knowledge, this is the first reported active adrenalitis of this type. It should be the precursor lesion of the adrenal calcifying fibrous tumor that was reported once before.
一位 67 岁男性因肿瘤(大小为 100mm)接受了肾上腺切除术。标本显示存在炎症,伴有轻微纤维化和中等程度的淋巴细胞和浆细胞浸润,免疫组化 IgG 和 IgG4 阳性,最终诊断为活动性 IgG4 相关的肾上腺炎。据我们所知,这是首例此类报道。它应该是之前报道过的肾上腺钙化纤维瘤的前驱病变。