Finley R
Centre for Food-borne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada, Guelph, ON.
Can Commun Dis Rep. 2014 Nov 7;40(Suppl 2):23-28. doi: 10.14745/ccdr.v40is2a04.
To describe patterns of antibiotic purchasing by Canadian hospitals from five regions in Canada between 2007 and 2011.
The Canadian Drugstore and Hospital Purchases Audit (CDH) dataset measures the dollar value and unit volume of pharmaceutical products from over 700 hospitals and is extrapolated to represent purchases by more than 800 hospitals in Canada. General population information was used for developing the rates of purchasing with a primary focus on unit volume.
In 2011, there was a 7% increase in total antibiotics purchased by Canadian hospitals compared to 2010, with slight increases in the purchasing levels for oral (8% increase) and parenteral (3% increase) antibiotics. Antibiotics considered of very high importance to human medicine (Category I) continued to represent a high proportion of the total antibiotics used in hospitals in 2011. Overall, consumption of antibiotics was highest in Manitoba at 2.61 doses per 1,000 inhabitants per day (DID), while Ontario had the lowest levels of consumption (1.26 DID). New Brunswick had the highest proportion of Category I consumption (43%, 0.62/1.43 DID) for 2011, driven by higher levels of fluoroquinolones consumed in that province.
Canadian hospitals have purchased an increasing number of antibiotics and are consuming slightly more oral and parenteral antibiotics. Overall, consumption was highest in Manitoba and total cost was highest in British Columbia. Ontario had the lowest level of consumption of anitbiotics and the lowest overall cost.
描述2007年至2011年加拿大五个地区医院的抗生素采购模式。
加拿大药店和医院采购审计(CDH)数据集衡量了700多家医院药品的美元价值和单位数量,并进行外推以代表加拿大800多家医院的采购情况。使用一般人群信息来制定采购率,主要关注单位数量。
与2010年相比,2011年加拿大医院购买的抗生素总量增加了7%,口服抗生素(增加8%)和注射用抗生素(增加3%)的采购量略有增加。对人类医学非常重要的抗生素(I类)在2011年医院使用的抗生素总量中仍占很高比例。总体而言,马尼托巴省的抗生素消费量最高,为每1000名居民每天2.61剂(DID),而安大略省的消费量最低(1.26 DID)。新不伦瑞克省2011年I类抗生素消费比例最高(43%,0.62/1.43 DID),该省氟喹诺酮类药物消费量较高。
加拿大医院购买的抗生素数量不断增加,口服和注射用抗生素的消费量略有增加。总体而言,马尼托巴省的消费量最高,不列颠哥伦比亚省的总成本最高。安大略省的抗生素消费量最低,总成本也最低。